Compile Data Set for Download or QSAR
maximum 50k data
Found 69 Enz. Inhib. hit(s) with all data for entry = 50030219
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292694((1R,2S)-1-(3-fluoro-4-((2-(pyridin-3-yl)quinolin-4...)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26524((1R,2S)-1-({3-fluoro-4-[(2-phenylquinolin-4-yl)met...)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292693((1R,2S)-1-(3-fluoro-4-((2-(1-methyl-1H-pyrazol-3-y...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292691((1R,2S)-1-(3-fluoro-4-((2-(pyrrolidin-1-yl)quinoli...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26525((1S,2R)-1-N-hydroxy-2-({4-[(2-phenylquinolin-4-yl)...)
Affinity DataKi:  0.180nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292690((1R,2S)-1-(3-fluoro-4-((2-morpholinoquinolin-4-yl)...)
Affinity DataKi:  0.210nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292688((1S,2R)-N-hydroxy-2-((S)-3-hydroxypyrrolidine-1-ca...)
Affinity DataKi:  0.25nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292689((1R,2S)-N2-hydroxy-N1,N1-dimethyl-1-(4-((2-phenylq...)
Affinity DataKi:  0.280nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292681((1S,2R)-N-hydroxy-2-((S)-2-(hydroxymethyl)pyrrolid...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292682((1R,2S)-1-(3-fluoro-4-((2-phenylquinolin-4-yl)meth...)
Affinity DataKi:  0.360nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292687((1S,2R)-2-((R)-3-(dimethylamino)pyrrolidine-1-carb...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292686((1S,2R)-2-((S)-3-(dimethylamino)pyrrolidine-1-carb...)
Affinity DataKi:  0.540nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292685((1R,2S)-N2-hydroxy-1-(4-((2-phenylquinolin-4-yl)me...)
Affinity DataKi:  0.630nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292692((1R,2S)-1-(3-fluoro-4-((2-(methylamino)quinolin-4-...)
Affinity DataKi:  0.760nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292695((1R,2S)-1-(4-((2-ethylquinolin-4-yl)methoxy)benzyl...)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292699((1R,2S)-ethyl 1-(4-((2-ethylquinolin-4-yl)methoxy)...)
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM23487((1S,2R)-1-N-hydroxy-2-({4-[(2-methylquinolin-4-yl)...)
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292700((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-(trifl...)
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292680((1S,2R)-2-cyano-N-hydroxy-2-(4-((2-phenylquinolin-...)
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292703((1R,2S)-ethyl 1-(3-fluoro-4-((2-methylquinolin-4-y...)
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292684((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-methyl...)
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292683((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenyl...)
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292698((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-isobut...)
Affinity DataKi:  18nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292697((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-(pyrid...)
Affinity DataKi:  22nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292696((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenyl...)
Affinity DataKi:  37nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292702((1R,2S)-ethyl 1-(3-chloro-4-((2-methylquinolin-4-y...)
Affinity DataKi:  158nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292701((1R,2S)-ethyl 1-(3-bromo-4-((2-methylquinolin-4-yl...)
Affinity DataKi:  381nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26524((1R,2S)-1-({3-fluoro-4-[(2-phenylquinolin-4-yl)met...)
Affinity DataKi: <1.40E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM23487((1S,2R)-1-N-hydroxy-2-({4-[(2-methylquinolin-4-yl)...)
Affinity DataKi:  5.80E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM23487((1S,2R)-1-N-hydroxy-2-({4-[(2-methylquinolin-4-yl)...)
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26524((1R,2S)-1-({3-fluoro-4-[(2-phenylquinolin-4-yl)met...)
Affinity DataKi:  1.28E+5nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292684((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-methyl...)
Affinity DataKi:  9.52E+5nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM23487((1S,2R)-1-N-hydroxy-2-({4-[(2-methylquinolin-4-yl)...)
Affinity DataKi:  1.00E+6nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292684((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-methyl...)
Affinity DataKi:  1.50E+6nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26524((1R,2S)-1-({3-fluoro-4-[(2-phenylquinolin-4-yl)met...)
Affinity DataKi:  2.27E+6nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM23487((1S,2R)-1-N-hydroxy-2-({4-[(2-methylquinolin-4-yl)...)
Affinity DataKi:  2.40E+6nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26524((1R,2S)-1-({3-fluoro-4-[(2-phenylquinolin-4-yl)met...)
Affinity DataKi:  4.07E+6nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292682((1R,2S)-1-(3-fluoro-4-((2-phenylquinolin-4-yl)meth...)
Affinity DataKi:  4.62E+6nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292684((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-methyl...)
Affinity DataKi:  7.00E+6nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292683((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenyl...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292684((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-methyl...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292681((1S,2R)-N-hydroxy-2-((S)-2-(hydroxymethyl)pyrrolid...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292680((1S,2R)-2-cyano-N-hydroxy-2-(4-((2-phenylquinolin-...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292682((1R,2S)-1-(3-fluoro-4-((2-phenylquinolin-4-yl)meth...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292680((1S,2R)-2-cyano-N-hydroxy-2-(4-((2-phenylquinolin-...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292681((1S,2R)-N-hydroxy-2-((S)-2-(hydroxymethyl)pyrrolid...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292682((1R,2S)-1-(3-fluoro-4-((2-phenylquinolin-4-yl)meth...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26524((1R,2S)-1-({3-fluoro-4-[(2-phenylquinolin-4-yl)met...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM23487((1S,2R)-1-N-hydroxy-2-({4-[(2-methylquinolin-4-yl)...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50292683((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenyl...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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