Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 50030249
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293171((1R,2S,4S,6E,8S,11R,12R,13S,14R,15R,22R)-13-hydrox...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293172((1R,2S,4S,6E,8S,11R,12R,13S,14R,15R,22R)-13-hydrox...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293169(CHEMBL523927 | kendomycin)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293170((1R,12S,16S,19R,20R,21S,22R)-4,8,21-Trihydroxy-10-...)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293169(CHEMBL523927 | kendomycin)
Affinity DataKd:  1.83E+6nMAssay Description:Inhibition of interaction between Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataKd:  3.38E+5nMAssay Description:Inhibition of interaction between Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataKd:  1.71E+3nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293171((1R,2S,4S,6E,8S,11R,12R,13S,14R,15R,22R)-13-hydrox...)
Affinity DataKd:  3.77E+5nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293170((1R,12S,16S,19R,20R,21S,22R)-4,8,21-Trihydroxy-10-...)
Affinity DataKd:  1.08E+7nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293169(CHEMBL523927 | kendomycin)
Affinity DataKd:  5.28E+5nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293171((1R,2S,4S,6E,8S,11R,12R,13S,14R,15R,22R)-13-hydrox...)
Affinity DataKd:  3.99E+5nMAssay Description:Inhibition of interaction between Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed