Compile Data Set for Download or QSAR
maximum 50k data
Found 51 Enz. Inhib. hit(s) with all data for entry = 50027452
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139601(1-(4-bromo-3-(trifluoromethyl)phenyl)-3-(4-(2-(met...)
Affinity DataIC50:  6nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  12nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139614(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  26nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249245(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  44nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139597(4-(4-(3-(2-methoxy-5-(trifluoromethyl)phenyl)ureid...)
Affinity DataIC50:  53nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139596(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  73nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249276(4-(4-(3-(4-chloro-2-methoxy-5-(trifluoromethyl)phe...)
Affinity DataIC50:  88nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249376(1-(3-tert-butylisoxazol-5-yl)-3-(4-(pyridin-4-ylox...)
Affinity DataIC50:  120nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139609(3-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenoxy)...)
Affinity DataIC50:  120nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249277(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  160nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139604(1-(5-tert-Butyl-isoxazol-3-yl)-3-[4-(pyridin-4-ylo...)
Affinity DataIC50:  230nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249278(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  230nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249279(1-(3-methoxyphenyl)-3-(4-(pyridin-4-yloxy)phenyl)u...)
Affinity DataIC50:  440nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249313(1-(5-tert-butylisoxazol-3-yl)-3-(4-(4-methoxypheno...)
Affinity DataIC50:  500nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249409(1-(5-tert-butylisoxazol-3-yl)-3-(4-(pyridin-4-ylme...)
Affinity DataIC50:  590nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249377(1-(5-tert-butylisoxazol-3-yl)-3-(2,3-dimethyl-4-ph...)
Affinity DataIC50:  650nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249346(1-(5-tert-butylisoxazol-3-yl)-3-(4-(3-methoxypheno...)
Affinity DataIC50:  700nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249406(1-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-3-(4-(py...)
Affinity DataIC50:  800nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249347(1-(4-(3-acetylphenoxy)phenyl)-3-(5-tert-butylisoxa...)
Affinity DataIC50:  820nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249310(1-(3-tert-butylphenyl)-3-(4-(pyridin-4-yloxy)pheny...)
Affinity DataIC50:  870nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249348(1-(5-tert-butylisoxazol-3-yl)-3-(4-(m-tolyloxy)phe...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105619(1-(5-tert-Butyl-isoxazol-3-yl)-3-(4-phenoxy-phenyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249349(4-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenoxy)...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249408(1-(5-tert-butylisoxazol-3-yl)-3-(2-methyl-4-phenox...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249444(1-(5-tert-butylisoxazol-3-yl)-3-(4-(hydroxy(pyridi...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095399(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105597(5-tert-Butyl-3-[3-(5-ethyl-[1,3,4]thiadiazol-2-yl)...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249311(1-(3-chloro-2-methoxyphenyl)-3-(4-(pyridin-4-yloxy...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095428(5-tert-Butyl-3-(3-p-tolyl-ureido)-1H-pyrrole-2-car...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105612(5-Isopropyl-3-(3-p-tolyl-ureido)-thiophene-2-carbo...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249312(1-(2-methoxy-4-nitrophenyl)-3-(4-(pyridin-4-yloxy)...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237709(4-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenoxy)...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095430(5-tert-Butyl-1-methyl-3-(3-p-tolyl-ureido)-1H-pyrr...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105599(5-Bromomethyl-3-(3-p-tolyl-ureido)-thiophene-2-car...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105613(5-tert-Butyl-3-[3-(1-methyl-1H-pyrazol-3-yl)-ureid...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249374(3-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenoxy)...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105598(5-tert-Butyl-3-[3-(1-ethyl-1H-pyrrol-3-yl)-ureido]...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105596(5-tert-Butyl-3-[3-(1-ethyl-1H-pyrazol-3-yl)-ureido...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105614(5-tert-Butyl-3-[3-(1-isopropyl-1H-pyrrol-3-yl)-ure...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249407(1-(5-tert-butylisoxazol-3-yl)-3-(4-phenoxy-3-(trif...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249375(CHEMBL470529 | N-(3-(4-(3-(5-tert-butylisoxazol-3-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105604(5-tert-Butyl-3-[3-(5-tert-butyl-[1,3,4]thiadiazol-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105607(5-tert-Butyl-3-[3-(3,4-dichloro-phenyl)-ureido]-1H...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105611(1-(2-(aminomethyl)-5-tert-butylthiophen-3-yl)-3-p-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105618(1-(5-tert-butyl-2-(dimethylcarbamoyl)thiophen-3-yl...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105608(5-tert-Butyl-3-[3-(1-isopropyl-1H-pyrazol-3-yl)-ur...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095423(5-tert-Butyl-3-(3-phenyl-ureido)-thiophene-2-carbo...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095411(5-tert-Butyl-3-[3-(4-hydroxy-phenyl)-ureido]-thiop...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105603(5-tert-Butyl-3-[3-(3,4-dichloro-phenyl)-ureido]-th...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105616(5-tert-Butyl-3-(3-m-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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