Compile Data Set for Download or QSAR
maximum 50k data
Found 72 Enz. Inhib. hit(s) with all data for entry = 50027529
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256157(CHEMBL481894 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  350nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256061(CHEMBL482160 | GNF-Pf-4399 | N-((5-chloro-8-hydrox...)
Affinity DataIC50:  460nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256102(CHEMBL480567 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  490nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256700(2-(N-methyl-N-phenylamino)-N-((5-chloro-8-hydroxyq...)
Affinity DataIC50:  560nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256160(CHEMBL481896 | N-((5-bromo-8-hydroxyquinolin-7-yl)...)
Affinity DataIC50:  620nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256062(CHEMBL482170 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  620nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256005(2-(benzyloxy)-N-((5-chloro-8-hydroxyquinolin-7-yl)...)
Affinity DataIC50:  700nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255999(CHEMBL474607 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  760nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256312(2-(p-tolyloxy)-N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  770nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256660(2-(N-methyl-N-phenylamino)-N-((5-chloro-8-hydroxyq...)
Affinity DataIC50:  780nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255970(CHEMBL482073 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  780nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256214(CHEMBL514963 | N-((5-bromo-8-hydroxyquinolin-7-yl)...)
Affinity DataIC50:  800nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256701(2-(N-benzyl-N-methylamino)-N-((5-chloro-8-hydroxyq...)
Affinity DataIC50:  820nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256105(CHEMBL482362 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  830nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256060(CHEMBL481506 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  830nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256063(2-(benzyloxy)-N-((5-chloro-8-hydroxyquinolin-7-yl)...)
Affinity DataIC50:  830nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256313(2-(4-methoxyphenoxy)-N-((5-chloro-8-hydroxyquinoli...)
Affinity DataIC50:  940nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256215(CHEMBL475265 | N-((2-chlorophenyl)(8-hydroxy-5-nit...)
Affinity DataIC50:  940nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255973(CHEMBL475436 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  990nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256059(CHEMBL481505 | GNF-PF-3875 | N-((5-chloro-8-hydrox...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256611(2-(4-cyanophenylamino)-N-((5-chloro-8-hydroxyquino...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256499(2-(4-chlorophenoxy)-N-((5-chloro-8-hydroxyquinolin...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256662(2-(4-acetylphenylamino)-N-((5-chloro-8-hydroxyquin...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256610(2-(4-acetylphenylamino)-N-((5-chloro-8-hydroxyquin...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256698(2-(4-chloro-3-methylphenylamino)-N-((5-chloro-8-hy...)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256158(CHEMBL519950 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256103(CHEMBL482360 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256740(2-(N-methyl-N-phenylamino)-N-((5-chloro-8-hydroxyq...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256661(2-(benzyl(methyl)amino)-N-((5-chloro-8-hydroxyquin...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255974(2-(benzyl(methyl)amino)-N-((5-chloro-8-hydroxyquin...)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256216(CHEMBL475770 | N-((8-hydroxy-5-methylquinolin-7-yl...)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256500(2-(3-(dimethylamino)phenoxy)-N-((5-chloro-8-hydrox...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255969(CHEMBL521273 | N-((8-hydroxy-5-nitroquinolin-7-yl)...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256738(2-(4-chloro-3-methylphenylamino)-N-((5-chloro-8-hy...)
Affinity DataIC50:  1.43E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256741(2-(N-benzyl-N-methylamino)-N-((5-chloro-8-hydroxyq...)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255971(2-(4-chloro-3-methylphenylamino)-N-((5-chloro-8-hy...)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256613(2-(4-chloro-3-methylphenylamino)-N-((5-chloro-8-hy...)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256376(CHEMBL519468 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256314(2-(3-(dimethylamino)phenoxy)-N-((5-chloro-8-hydrox...)
Affinity DataIC50:  1.67E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256739(2-(benzylamino)-N-((5-chloro-8-hydroxyquinolin-7-y...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256556(2-(3-(dimethylamino)phenoxy)-N-((5-chloro-8-hydrox...)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256659(2-(benzylamino)-N-((5-chloro-8-hydroxyquinolin-7-y...)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256104(CHEMBL482361 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255972(2-(benzylamino)-N-((5-chloro-8-hydroxyquinolin-7-y...)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256102(CHEMBL480567 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of ADAMTS4 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256429(2-(p-tolyloxy)-N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256612(2-(3-(dimethylamino)phenylamino)-N-((5-chloro-8-hy...)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255967(CHEMBL481574 | N-((8-hydroxyquinolin-7-yl)(phenyl)...)
Affinity DataIC50:  2.28E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256159(CHEMBL481895 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  2.32E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256426(2-(4-Acetyl-phenoxy)-N-[(5-chloro-8-hydroxy-quinol...)
Affinity DataIC50:  2.33E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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