Compile Data Set for Download or QSAR
maximum 50k data
Found 68 Enz. Inhib. hit(s) with all data for entry = 50038781
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50225074((1S,3S,5S)-2-[(S)-2-amino-2-(3-hydroxy-adamantan-1...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50050525((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Affinity DataKi:  2nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276467((1R,3R,5R)-2-((2S,4S)-4-(3-chloro-4-cyanophenylami...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50173963((2S,4S)-1-((R)-2-amino-3-(4-methoxybenzylsulfonyl)...)
Affinity DataKi:  53nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50050525((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Affinity DataKi:  125nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM11463(CHEMBL22310 | N-{4-[(1S)-1-amino-2-[(3S)-3-fluorop...)
Affinity DataKi:  4.90E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50:  0.0120nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  0.0640nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50166318((S)-1-[(2S,4S)-4-(3-Chloro-4-cyano-phenylamino)-py...)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of DPP4 in rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50166319(4-[(3S,5S)-5-((S)-2-Cyano-pyrrolidine-1-carbonyl)-...)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50166318((S)-1-[(2S,4S)-4-(3-Chloro-4-cyano-phenylamino)-py...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50166319(4-[(3S,5S)-5-((S)-2-Cyano-pyrrolidine-1-carbonyl)-...)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of DPP4 in rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276653((S)-2-(4-(((S)-1-((R)-3-amino-4-(2,5-difluoropheny...)
Affinity DataIC50:  0.480nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276423((2S,4S)-1-((2S,3S)-2-amino-3-methylpentanoyl)-4-fl...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276700(3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methox...)
Affinity DataIC50:  2.28nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Mus musculus)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276520((2R,4R)-4-fluoro-1-(2-(4-methyl-1-(methylsulfonyl)...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of mouse DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50151005((S)-1-((S)-7-Methoxy-1,2,3,4-tetrahydro-isoquinoli...)
Affinity DataIC50:  4nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276598((2S,3S)-3-amino-2-(4-(1,8a-dihydro-[1,2,4]triazolo...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50242513((2S,4S)-4-Fluoro-1-[N-(2-hydroxy-1,1-dimethylethyl...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50205136((2S)-1-{[(2S,4R)-4-(3-hydroxy-2,6-dimethylphenyl)-...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276520((2R,4R)-4-fluoro-1-(2-(4-methyl-1-(methylsulfonyl)...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276652(2-(adamantan-1-ylamino)-1-[(2R)-2-(dihydroxyborany...)
Affinity DataIC50:  8nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276654(3-methyl-7-(3-methylbut-2-enyl)-8-((3aS,6aR)-octah...)
Affinity DataIC50:  18nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM11113(6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl...)
Affinity DataIC50:  22nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276519((2R,4R)-1-((S)-2-amino-3,3-bis(4-fluorophenyl)prop...)
Affinity DataIC50:  22nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50:  24nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50198863(6-((3S,5S)-5-(thiazolidine-3-carbonyl)pyrrolidin-3...)
Affinity DataIC50:  25.4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50198863(6-((3S,5S)-5-(thiazolidine-3-carbonyl)pyrrolidin-3...)
Affinity DataIC50:  30.4nMAssay Description:Inhibition of DPP4 in rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)
Affinity DataIC50:  34nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276652(2-(adamantan-1-ylamino)-1-[(2R)-2-(dihydroxyborany...)
Affinity DataIC50:  46nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM11463(CHEMBL22310 | N-{4-[(1S)-1-amino-2-[(3S)-3-fluorop...)
Affinity DataIC50:  48nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50:  69nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  86nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50137251(CHEMBL264738 | N-(4-((S)-1-amino-2-oxo-2-(pyrrolid...)
Affinity DataIC50:  88nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  88nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50: >100nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276520((2R,4R)-4-fluoro-1-(2-(4-methyl-1-(methylsulfonyl)...)
Affinity DataIC50:  100nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50151843((R)-3-Amino-1-((R)-2-benzyl-piperazin-1-yl)-4-(2-f...)
Affinity DataIC50:  139nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50150854(6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276465((3R)-3-amino-4-((S)-2-cyanopyrrolidin-1-yl)-N-(2,2...)
Affinity DataIC50:  251nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM12191((2S)-2-amino-2-cyclohexyl-1-(pyrrolidin-1-yl)ethan...)
Affinity DataIC50:  320nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50237207((2S)-3-(3-(2-chloro-4-(methylsulfonyl)phenyl)-1,2,...)
Affinity DataIC50:  330nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276652(2-(adamantan-1-ylamino)-1-[(2R)-2-(dihydroxyborany...)
Affinity DataIC50:  420nMAssay Description:Inhibition of DPP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM11464((2S,3S)-2-amino-3-methyl-1-(1,3-thiazolidin-3-yl)p...)
Affinity DataIC50:  420nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50150854(6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...)
Affinity DataIC50:  490nMAssay Description:Inhibition of pig kidney DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50150854(6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...)
Affinity DataIC50:  780nMAssay Description:Inhibition of DPP4 in rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM11463(CHEMBL22310 | N-{4-[(1S)-1-amino-2-[(3S)-3-fluorop...)
Affinity DataIC50:  993nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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