Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 50030411
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295781(CHEMBL554525 | N-(3-(tert-butyl(isopropyl)amino)-2...)
Affinity DataEC50:  1.66E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50414476(CHEMBL2021569)
Affinity DataEC50:  2.86E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295783(CHEMBL549427 | N-(3-(ethyl(propyl)amino)-2-hydroxy...)
Affinity DataEC50:  2.30E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295784(CHEMBL560657 | N-(3-(dibutylamino)-2-hydroxypropox...)
Affinity DataEC50:  2.09E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295785(CHEMBL552321 | N-(3-(dipropylamino)-2-hydroxypropo...)
Affinity DataEC50:  2.39E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295786(CHEMBL552320 | N-(3-(diethylamino)-2-hydroxypropox...)
Affinity DataEC50:  2.71E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295787(CHEMBL557917 | N-(3-(2,6-dimethylpiperidin-1-yl)-2...)
Affinity DataEC50:  3.24E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295788(CHEMBL561119 | N-(3-(3,5-dimethylpiperidin-1-yl)-2...)
Affinity DataEC50:  1.74E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295789(CHEMBL570771 | N-(3-(3-fluoropiperidin-1-yl)-2-hyd...)
Affinity DataEC50:  5.26E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295790(CHEMBL550790 | N-(2-hydroxy-3-(pyrrolidin-1-yl)pro...)
Affinity DataEC50:  6.28E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295791(CHEMBL552259 | N-(2-hydroxy-3-(piperidin-1-yl)prop...)
Affinity DataEC50:  5.26E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295792(CHEMBL550179 | N-(2-hydroxy-3-(piperidin-1-yl)prop...)
Affinity DataEC50:  4.17E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295793(CHEMBL551057 | N-(2-hydroxy-3-(piperidin-1-yl)prop...)
Affinity DataEC50:  1.21E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295794(6-(N,N-dimethylsulfamoyl)-N-(2-hydroxy-3-(piperidi...)
Affinity DataEC50:  4.16E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295795(5-(ethylsulfonyl)-N-(2-hydroxy-3-(piperidin-1-yl)p...)
Affinity DataEC50:  4.29E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295796(6-chloro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)be...)
Affinity DataEC50:  2.29E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295797(5-chloro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)be...)
Affinity DataEC50:  2.09E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295798(CHEMBL550653 | N-(2-hydroxy-3-(piperidin-1-yl)prop...)
Affinity DataEC50:  3.10E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295799(CHEMBL564701 | N-(2-hydroxy-3-(piperidin-1-yl)prop...)
Affinity DataEC50:  4.16E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295800(7-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)be...)
Affinity DataEC50:  1.85E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295801(4-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)be...)
Affinity DataEC50:  2.02E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295802(6-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)be...)
Affinity DataEC50:  2.94E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295803(5-fluoro-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)be...)
Affinity DataEC50:  5.13E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295804(CHEMBL564532 | N-(3-((cyclopropylmethyl)(isopropyl...)
Affinity DataEC50:  1.24E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295805(CHEMBL560380 | N-(3-((3-fluoropropyl)(isopropyl)am...)
Affinity DataEC50:  2.28E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295806(CHEMBL561724 | N-(2-hydroxy-3-((2-hydroxyethyl)(is...)
Affinity DataEC50:  2.87E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295807((S)-N-(2-hydroxy-3-(isopropyl(propyl)amino)propoxy...)
Affinity DataEC50:  2.41E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50414475(CHEMBL2021570)
Affinity DataEC50:  3.19E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50295782(CHEMBL558309 | N-(3-(diisopropylamino)-2-hydroxypr...)
Affinity DataEC50:  2.55E+4nMAssay Description:Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed