Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50033476
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50100436(CHEMBL412768 | NH2-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val...)
Affinity DataIC50:  120nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50329115(2-(6-(4,6-di(piperidin-1-yl)-1,3,5-triazin-2-ylami...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346130(CHEMBL1782314)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346135(2-(6-(4,6-di(piperidin-1-yl)-1,3,5-triazin-2-ylami...)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346137(CHEMBL1782321 | N1,N6-bis(3-cyano-4,5,6,7,8,9-hexa...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346133(2-(3-cyano-4,6-diphenylpyridin-2-ylthio)-N-(3-nitr...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346134(2-(4-methyl-5-(2-oxo-2-(4-phenylthiazol-2-ylamino)...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346125(CHEMBL1782310 | N-((4,6-dimethylpyrimidin-2-ylamin...)
Affinity DataIC50:  2.86E+4nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346136(2-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl...)
Affinity DataIC50:  3.45E+4nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346128(2-(4-(4-chlorophenyl)-3-cyano-6-(4-methoxyphenyl)p...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346127(2-(3-cyano-6-(4-fluorophenyl)-4-phenylpyridin-2-yl...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346132(4-bromo-N-(4-bromophenylsulfonyl)-N-(1-(3,4-dichlo...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346124(CHEMBL1782309 | N-(5-(2,3-dichlorobenzyl)thiazol-2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346131(2-(5-((1H-indol-3-yl)methyl)-4-benzyl-4H-1,2,4-tri...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346129(3-(benzylthio)-6-(5-chloro-3-methyl-1-phenyl-1H-py...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346126(CHEMBL1782311 | N-Adamantan-1-yl-2-[3-cyano-4-(4-f...)
Affinity DataIC50:  1.18E+5nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed