Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 50038923
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50369748(CHEMBL208599)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50:  1.84nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298409((+/-)-3-chloro-6,7,10,11-tetrahydro-N-(2-(4-(6-(3,...)
Affinity DataIC50:  3.95nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298408((+/-)-3-chloro-6,7,10,11-tetrahydro-N-(2-(4-(6-(3,...)
Affinity DataIC50:  5.96nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298403((+/-)-N-(2-Hydroxyethyl)-3-chloro-6,7,10,11-tetrah...)
Affinity DataIC50:  6.75nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298405((+/-)-N-(2-azidoethyl)-3-chloro-6,7,10,11-tetrahyd...)
Affinity DataIC50:  8.69nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298402((+/-)-N-(2-Hydroxyethyl)-3-chloro-6,7,10,11-tetrah...)
Affinity DataIC50:  9.66nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298406((+/-)-N-(2-azidoethyl)-3-chloro-6,7,10,11-tetrahyd...)
Affinity DataIC50:  13.7nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298404((+/-)-N-(2-chloroethyl)-3-chloro-6,7,10,11-tetrahy...)
Affinity DataIC50:  43.3nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298407((+/-)-11-Amino-8-methyl-5,6,9,10-tetrahydro-6,10-m...)
Affinity DataIC50:  342nMAssay Description:Inhibition of human recombinant BuChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298388((+/-)-11-Amino-8-ethyl-5,6,9,10-tetrahydro-6,10-me...)
Affinity DataIC50:  664nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298407((+/-)-11-Amino-8-methyl-5,6,9,10-tetrahydro-6,10-m...)
Affinity DataIC50:  810nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298406((+/-)-N-(2-azidoethyl)-3-chloro-6,7,10,11-tetrahyd...)
Affinity DataIC50:  824nMAssay Description:Inhibition of human recombinant BuChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298387((+/-)-11-Amino-8-ethyl-5,6,9,10-tetrahydro-6,10-me...)
Affinity DataIC50:  855nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298405((+/-)-N-(2-azidoethyl)-3-chloro-6,7,10,11-tetrahyd...)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of human recombinant BuChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298398((+/-)-2-Chloro-N-(3-chloro-6,7,10,11-tetrahydro-12...)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298410(1-(4-nitrophenyl)-6,7-dimethoxy-2-(oct-7-ynyl)-1,2...)
Affinity DataIC50:  2.92E+3nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298403((+/-)-N-(2-Hydroxyethyl)-3-chloro-6,7,10,11-tetrah...)
Affinity DataIC50:  3.64E+3nMAssay Description:Inhibition of human recombinant BuChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298389((+/-)-9-Amino-7-methyl-2,3-dimethylfuro[2,3-b]-4,5...)
Affinity DataIC50:  4.78E+3nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298413((+/-)-12-Amino-2,3-dimethoxy-9-ethyl-6,7,10,11-tet...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298390((+/-)-9-Amino-7-ethyl-2,3-dimethylfuro[2,3-b]-4,5,...)
Affinity DataIC50:  6.45E+3nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298395((+/-)-11-Amino-2-thiopropyl-5,6,9,10-tetrahydro-th...)
Affinity DataIC50:  7.27E+3nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298394((+/-)-11-Amino-2-thiopropyl-5,6,9,10-tetrahydro-th...)
Affinity DataIC50:  7.69E+3nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298411(1-(3-nitrophenyl)-6,7-dimethoxy-2-(oct-7-ynyl)-1,2...)
Affinity DataIC50:  8.08E+3nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298412((+/-)-12-Amino-2,3-dimethoxy-9-methyl-6,7,10,11-te...)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298399((+/-)-3-Chloro-12-hydroxy-6,7,10,11-tetrahydro-9-m...)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298401((+/-)-3,12-Dichloro-6,7,10,11-tetrahydro-9-ethyl-7...)
Affinity DataIC50:  1.92E+4nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298400((+/-)-3,12-Dichloro-6,7,10,11-tetrahydro-9-methyl-...)
Affinity DataIC50:  2.24E+4nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298393((+/-)-9-Amino-1-cyclobutyl-oxazolo[4,5-b]-6-methyl...)
Affinity DataIC50:  2.71E+4nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298392((+/-)-9-Amino-1-cyclopropyl-oxazolo[4,5-b]-6-ethyl...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298396((+/-)-9-Amino-1-(methylthio)-1H-pyrazolo[3,4-b]-3,...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298397((+/-)-9-Amino-1H-pyrazolo[3,4-b]-3,4,7,8-tetrahydr...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cobra

Curated by ChEMBL
LigandPNGBDBM50298391((+/-)-9-Amino-1-cyclopropyl-oxazolo[4,5-b]-6-methy...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human recombinant AChE in erythrocytes by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed