Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 50031611
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316213(4-((3-(2-(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,...)
Affinity DataIC50:  0.400nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316212(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316210(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316202(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  5nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316205(CHEMBL1096889 | N-(2-(3-(2-(diisopropylamino)ethyl...)
Affinity DataIC50:  5nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316211(CHEMBL1096895 | N-(2-(3-(4-((diethylamino)methyl)b...)
Affinity DataIC50:  5nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316209(CHEMBL1096893 | N-(2-(3-benzylureido)ethyl)-6-(2,2...)
Affinity DataIC50:  6nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233816((2S,3S,4R,5R)-5-(2-((3-(2-(cyclopentyl(isopropyl)a...)
Affinity DataIC50:  6nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316204(CHEMBL1096888 | N-(2-(3-(2-(cyclopentyl(isopropyl)...)
Affinity DataIC50:  7nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316208(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  10nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316206(CHEMBL1096890 | N-(2-(3-(2-(3,4-dihydroisoquinolin...)
Affinity DataIC50:  10nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233809((2S,3S,4R,5R)-5-(6-(2,2-diphenylethylamino)-2-((3-...)
Affinity DataIC50:  17nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316203(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)te...)
Affinity DataIC50:  45nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233810(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-t...)
Affinity DataIC50:  65nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316207(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  305nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed