Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50030432
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296050(1-butyl-6-methyl-3-(5-methylthiophen-2-yl)pyrimido...)
Affinity DataEC50:  1.68E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296072(1-ethyl-6-methyl-3-(5-methylthiophen-2-yl)-5,7-dio...)
Affinity DataEC50:  1.16E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296052(1-butyl-6-methyl-3-(5-methylfuran-2-yl)pyrimido[5,...)
Affinity DataEC50:  9.90E+3nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296053(1-butyl-6-methyl-3-(5-methylfuran-2-yl)-5,7-dioxo-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296054(1-ethyl-6-methyl-3-(5-methylfuran-2-yl)pyrimido[5,...)
Affinity DataEC50:  4.63E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296055(1-ethyl-6-methyl-3-(5-methylfuran-2-yl)-5,7-dioxo-...)
Affinity DataEC50:  2.06E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296056(1-ethyl-3-(furan-2-yl)-6-methylpyrimido[5,4-e][1,2...)
Affinity DataEC50:  1.01E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296057(1-ethyl-6-methyl-3-(1H-pyrrol-2-yl)pyrimido[5,4-e]...)
Affinity DataEC50:  3.50E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296058(1-ethyl-6-methyl-5,7-dioxo-3-(1H-pyrrol-2-yl)-1,5,...)
Affinity DataEC50:  2.47E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296059(1-butyl-6-methyl-5,7-dioxo-3-(1H-pyrrol-2-yl)-1,5,...)
Affinity DataEC50:  1.49E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296060(1-ethyl-3-(1H-imidazol-2-yl)-6-methylpyrimido[5,4-...)
Affinity DataEC50:  3.98E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296061(1-butyl-3-(1H-imidazol-2-yl)-6-methylpyrimido[5,4-...)
Affinity DataEC50:  7.70E+3nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296062(1-butyl-6-methyl-3-(thiazol-2-yl)pyrimido[5,4-e][1...)
Affinity DataEC50:  2.10E+3nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296063(3-(1H-benzo[d]imidazol-2-yl)-1-butyl-6-methylpyrim...)
Affinity DataEC50:  4.08E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296064(1-butyl-6-methyl-3-(quinolin-2-yl)pyrimido[5,4-e][...)
Affinity DataEC50:  2.50E+3nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296065(3-(benzo[d]thiazol-2-yl)-1-butyl-6-methylpyrimido[...)
Affinity DataEC50:  2.50E+3nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296066(3-(benzo[d]thiazol-2-yl)-1-isopentyl-6-methylpyrim...)
Affinity DataEC50:  2.50E+3nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296067(3-(benzo[d]thiazol-2-yl)-1-isobutyl-6-methylpyrimi...)
Affinity DataEC50:  1.30E+3nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296068(3-(benzo[d]thiazol-2-yl)-1-benzyl-6-methylpyrimido...)
Affinity DataEC50:  4.10E+3nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296069(3-(benzo[d]thiazol-2-yl)-1-(4-fluorobenzyl)-6-meth...)
Affinity DataEC50:  1.40E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296070(1-butyl-6-methyl-3-phenylpyrimido[5,4-e][1,2,4]tri...)
Affinity DataEC50:  1.48E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50071058((2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,1...)
Affinity DataEC50:  1.10E+3nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50071058((2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,1...)
Affinity DataEC50:  2.60E+3nMAssay Description:Amplification of HSF1 transcriptional activity in human HeLa cells assessed as granule formation pretreated for 3 hrs by immunocytochemical stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM31044(1-Ethyl-6-methyl-3-thiophen-2-yl-1H-pyrimido[5,4-e...)
Affinity DataEC50:  5.10E+3nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296071(1-ethyl-6-methyl-3-(5-methylthiophen-2-yl)pyrimido...)
Affinity DataEC50:  1.73E+4nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cytrx

Curated by ChEMBL
LigandPNGBDBM50296051(1-butyl-6-methyl-3-(5-methylthiophen-2-yl)-5,7-dio...)
Affinity DataEC50:  8.60E+3nMAssay Description:Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed