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Found 24 Enz. Inhib. hit(s) with all data for entry = 50030295
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293820(2-(2-(2-amino-6-oxo-1,6,7,8-tetrahydropurin-9-yl)e...)
Affinity DataKi:  1.00E+3nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293821(2-(2-(6-oxo-1,6,7,8-tetrahydropurin-9-yl)ethoxy)et...)
Affinity DataKi:  3.60E+3nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293826((2-(4-oxo-2,3,4,5-tetrahydropyrazolo[3,4-d]pyrimid...)
Affinity DataKi:  4.30E+3nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293819(((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1,6,7,8-tetr...)
Affinity DataKi:  5.40E+3nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293818(((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6,7,8-tetrahydro...)
Affinity DataKi:  5.80E+3nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293830(CHEMBL561493 | RS-(3-(2-amino-6-oxo-1,6,7,8-tetrah...)
Affinity DataKi:  5.90E+3nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293835((R)-5-(2-Amino-6-oxo-1,6,7,8-tetrahydro-purin-9-yl...)
Affinity DataKi:  1.23E+4nMpH: 8.5Assay Description:Inhibition of human recombinant HGPRT at pH 8.5 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293831((S)-(1-(5-amino-7-oxo-1,2,6,7-tetrahydro-[1,2,3]tr...)
Affinity DataKi:  1.50E+4nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293835((R)-5-(2-Amino-6-oxo-1,6,7,8-tetrahydro-purin-9-yl...)
Affinity DataKi:  1.90E+4nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293836(CHEMBL541006 | RS-(1-(2-amino-6-oxo-7,8-dihydro-1H...)
Affinity DataKi:  2.27E+4nMpH: 8.5Assay Description:Inhibition of human recombinant HGPRT at pH 8.5 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50225188((2-(2-amino-6-oxo-1,6,7,8-tetrahydropurin-9-yl)eth...)
Affinity DataKi:  2.90E+4nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293833(((R)-1-(2-amino-8-bromo-6-oxo-1,6,7,8-tetrahydropu...)
Affinity DataKi:  4.10E+4nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50225188((2-(2-amino-6-oxo-1,6,7,8-tetrahydropurin-9-yl)eth...)
Affinity DataKi:  5.59E+4nMpH: 8.5Assay Description:Inhibition of human recombinant HGPRT at pH 8.5 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293824((2-(2-amino-8-hydroxy-6-oxo-1,6,7,8-tetrahydropuri...)
Affinity DataKi:  6.80E+4nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293834((S)-5-(2-Amino-6-oxo-1,6,7,8-tetrahydro-purin-9-yl...)
Affinity DataKi:  9.00E+4nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293834((S)-5-(2-Amino-6-oxo-1,6,7,8-tetrahydro-purin-9-yl...)
Affinity DataKi:  1.15E+5nMpH: 8.5Assay Description:Inhibition of human recombinant HGPRT at pH 8.5 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293828(CHEMBL560759 | isopropyl(2-(2-amino-6-oxo-1,6,7,8-...)
Affinity DataKi:  1.40E+5nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293823((2-(5-amino-7-oxo-1,2,6,7-tetrahydro-[1,2,3]triazo...)
Affinity DataKi:  1.75E+5nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293837((S)-9-[3-hydroxy-2-(phosphonomethoxy)propyl]guanin...)
Affinity DataKi:  1.77E+5nMpH: 8.5Assay Description:Inhibition of human recombinant HGPRT at pH 8.5 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293838((2-(6-oxo-1,6,7,8-tetrahydropurin-9-yl)ethoxy)meth...)
Affinity DataKi:  1.82E+5nMpH: 8.5Assay Description:Inhibition of human recombinant HGPRT at pH 8.5 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293832(((S)-1-(2-amino-8-bromo-6-oxo-1,6,7,8-tetrahydropu...)
Affinity DataKi: >3.00E+5nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293825((2-(2-amino-8-bromo-6-oxo-1,6,7,8-tetrahydropurin-...)
Affinity DataKi: >4.00E+5nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293829(6-methylheptyl(2-(2-amino-6-oxo-1,6,7,8-tetrahydro...)
Affinity DataKi: >1.00E+6nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50293827((2-(2-amino-6-thioxo-1,6,7,8-tetrahydropurin-9-yl)...)
Affinity DataKi: >1.00E+6nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed