Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50032045
TargetEstrogen receptor(Homo sapiens (Human))
Institut FüR Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50323701(2-(Trifluoroacetyl)-1,2,3,4-tetrahydro-6-isoquinol...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]estradiol from human ERalpha ligand binding domain expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institut FüR Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50323700(CHEMBL1213616 | N-(2-(dimethylamino)ethyl)-4-((nap...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of LOX5 in human whole blood assessed as inhibition of conversion of aracidonic acid to leukotrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institut FüR Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50323699(2-(benzyloxy)naphthalene | 2-Benzyloxy-naphthalene...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of LOX5 in human whole blood assessed as inhibition of conversion of aracidonic acid to leukotrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Institut FüR Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50323701(2-(Trifluoroacetyl)-1,2,3,4-tetrahydro-6-isoquinol...)
Affinity DataEC50:  4.60E+3nMAssay Description:Binding affinity to human ERbeta ligand binding domain expressed in Escherichia coli BL21(DE3) cells assessed as recruitment of fluorescently labeled...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Institut FüR Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50323701(2-(Trifluoroacetyl)-1,2,3,4-tetrahydro-6-isoquinol...)
Affinity DataEC50:  275nMAssay Description:Binding affinity to human ERalpha ligand binding domain expressed in Escherichia coli BL21(DE3) cells assessed as recruitment of fluorescently labele...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed