Affinity DataKi: 2nMAssay Description:Displacement of [3H]estradiol from human ERalpha ligand binding domain expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institut FüR Molekulare Physiologie
Curated by ChEMBL
Institut FüR Molekulare Physiologie
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of LOX5 in human whole blood assessed as inhibition of conversion of aracidonic acid to leukotrineMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institut FüR Molekulare Physiologie
Curated by ChEMBL
Institut FüR Molekulare Physiologie
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of LOX5 in human whole blood assessed as inhibition of conversion of aracidonic acid to leukotrineMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Institut FüR Molekulare Physiologie
Curated by ChEMBL
Institut FüR Molekulare Physiologie
Curated by ChEMBL
Affinity DataEC50: 4.60E+3nMAssay Description:Binding affinity to human ERbeta ligand binding domain expressed in Escherichia coli BL21(DE3) cells assessed as recruitment of fluorescently labeled...More data for this Ligand-Target Pair
Affinity DataEC50: 275nMAssay Description:Binding affinity to human ERalpha ligand binding domain expressed in Escherichia coli BL21(DE3) cells assessed as recruitment of fluorescently labele...More data for this Ligand-Target Pair