Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50030485
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296914((1S,3R)-N-((2-(3-chloropyridin-2-yl)-5-isopropyl-1...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296914((1S,3R)-N-((2-(3-chloropyridin-2-yl)-5-isopropyl-1...)
Affinity DataIC50:  2.30nMAssay Description:Antagonist activity at human cloned ORL1 receptor expressed in CHO cells assessed as inhibition of nociceptin/orphanin FQ-stimulated [35S]GTPgammaS b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296912((1S,3R)-N-((2-(3-chloropyridin-2-yl)-5-ethyl-1-(6-...)
Affinity DataIC50:  2.30nMAssay Description:Antagonist activity at human cloned ORL1 receptor expressed in CHO cells assessed as inhibition of nociceptin/orphanin FQ-stimulated [35S]GTPgammaS b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296912((1S,3R)-N-((2-(3-chloropyridin-2-yl)-5-ethyl-1-(6-...)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296911((1S,3R)-N-((2-(3-chloropyridin-2-yl)-5-methyl-1-(6...)
Affinity DataIC50:  3.70nMAssay Description:Antagonist activity at human cloned ORL1 receptor expressed in CHO cells assessed as inhibition of nociceptin/orphanin FQ-stimulated [35S]GTPgammaS b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296915((1S,3R)-N-((1-(3,5-difluorophenyl)-5-isopropyl-2-m...)
Affinity DataIC50:  4.5nMAssay Description:Antagonist activity at human cloned ORL1 receptor expressed in CHO cells assessed as inhibition of nociceptin/orphanin FQ-stimulated [35S]GTPgammaS b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296913(CHEMBL561396 | N-((2-(3-chloropyridin-2-yl)-5-isop...)
Affinity DataIC50:  4.70nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296930((1S,3R)-N-((5-(4-chlorophenyl)-1-isopropyl-4-(2-me...)
Affinity DataIC50:  5.60nMAssay Description:Antagonist activity at human cloned ORL1 receptor expressed in CHO cells assessed as inhibition of nociceptin/orphanin FQ-stimulated [35S]GTPgammaS b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296930((1S,3R)-N-((5-(4-chlorophenyl)-1-isopropyl-4-(2-me...)
Affinity DataIC50:  7.60nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296915((1S,3R)-N-((1-(3,5-difluorophenyl)-5-isopropyl-2-m...)
Affinity DataIC50:  8.60nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296911((1S,3R)-N-((2-(3-chloropyridin-2-yl)-5-methyl-1-(6...)
Affinity DataIC50:  9.10nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296913(CHEMBL561396 | N-((2-(3-chloropyridin-2-yl)-5-isop...)
Affinity DataIC50:  9.60nMAssay Description:Antagonist activity at human cloned ORL1 receptor expressed in CHO cells assessed as inhibition of nociceptin/orphanin FQ-stimulated [35S]GTPgammaS b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296929(CHEMBL562663 | N-((5-(4-chlorophenyl)-1-isopropyl-...)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296910(CHEMBL554299 | N-((2-(3-chloropyridin-2-yl)-5-meth...)
Affinity DataIC50:  26nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296898(CHEMBL560875 | N-((1-(4-chlorophenyl)-2-(2,4-dichl...)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29968(arylpyrazole, 13)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296917(CHEMBL560937 | N-((5-(4-chlorophenyl)-4-(2,4-dichl...)
Affinity DataIC50:  33nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296928(CHEMBL557729 | N-((5-(4-chlorophenyl)-4-(2,4-dichl...)
Affinity DataIC50:  96nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296897(CHEMBL558524 | N-((5-(4-chlorophenyl)-1-(2,4-dichl...)
Affinity DataIC50:  130nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296923(CHEMBL564484 | N-((5-(4-chlorophenyl)-4-(2,4-dichl...)
Affinity DataIC50:  160nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296916(CHEMBL564837 | N-((5-(4-chlorophenyl)-4-(2,4-dichl...)
Affinity DataIC50:  160nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296925(CHEMBL554058 | N-((5-(4-chlorophenyl)-4-(2,4-dichl...)
Affinity DataIC50:  160nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296919(CHEMBL564225 | N-((5-(4-chlorophenyl)-1-cyclopropy...)
Affinity DataIC50:  190nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296905(CHEMBL562077 | N-((1-(4-chlorophenyl)-5-(2,4-dichl...)
Affinity DataIC50:  200nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296926(CHEMBL563073 | N-((5-(4-chlorophenyl)-4-(2,4-dichl...)
Affinity DataIC50:  500nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296899(CHEMBL550117 | N-((5-(4-chlorophenyl)-4-(2,4-dichl...)
Affinity DataIC50:  520nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296920(CHEMBL552011 | N-((5-(4-chlorophenyl)-1-cyclobutyl...)
Affinity DataIC50:  530nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296924(CHEMBL552417 | N-((5-(4-chlorophenyl)-4-(2,4-dichl...)
Affinity DataIC50:  540nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296901(CHEMBL550601 | N-((2-(4-chlorophenyl)-1-(2,4-dichl...)
Affinity DataIC50:  620nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296900(CHEMBL552482 | N-((4-(4-chlorophenyl)-5-(2,4-dichl...)
Affinity DataIC50:  850nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296909(CHEMBL555203 | N-((5-(3,5-difluorophenyl)-4-methyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296908(CHEMBL560798 | N-((1-(3,4-difluorophenyl)-5-methyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296907(CHEMBL553396 | N-((3,5-dimethyl-1-phenyl-1H-pyrazo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296906(CHEMBL559200 | N-((4-(4-chlorophenyl)-5-(2,4-dichl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296904(CHEMBL550602 | N-((5-(4-chlorophenyl)-1-(2,4-dichl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296922(CHEMBL551938 | N-((5-(4-chlorophenyl)-1-cyclohexyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296902(CHEMBL564966 | N-((5-(4-chlorophenyl)-4-(2,4-dichl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296927(CHEMBL556851 | N-((5-(4-chlorophenyl)-4-(2,4-dichl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296918(CHEMBL563726 | N-((1-tert-butyl-5-(4-chlorophenyl)...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296921(CHEMBL563158 | N-((5-(4-chlorophenyl)-1-cyclopenty...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296903(CHEMBL558453 | N-((5-(4-chlorophenyl)-4-(2,4-dichl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296929(CHEMBL562663 | N-((5-(4-chlorophenyl)-1-isopropyl-...)
Affinity DataIC50:  3.20E+3nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cells overexpressing Ikr channel proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296913(CHEMBL561396 | N-((2-(3-chloropyridin-2-yl)-5-isop...)
Affinity DataIC50:  9.90E+3nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cells overexpressing Ikr channel proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296912((1S,3R)-N-((2-(3-chloropyridin-2-yl)-5-ethyl-1-(6-...)
Affinity DataIC50:  1.50E+4nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cells overexpressing Ikr channel proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296914((1S,3R)-N-((2-(3-chloropyridin-2-yl)-5-isopropyl-1...)
Affinity DataIC50:  1.50E+4nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cells overexpressing Ikr channel proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296930((1S,3R)-N-((5-(4-chlorophenyl)-1-isopropyl-4-(2-me...)
Affinity DataIC50:  1.60E+4nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cells overexpressing Ikr channel proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296910(CHEMBL554299 | N-((2-(3-chloropyridin-2-yl)-5-meth...)
Affinity DataIC50:  1.90E+4nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cells overexpressing Ikr channel proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296911((1S,3R)-N-((2-(3-chloropyridin-2-yl)-5-methyl-1-(6...)
Affinity DataIC50:  3.10E+4nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cells overexpressing Ikr channel proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296915((1S,3R)-N-((1-(3,5-difluorophenyl)-5-isopropyl-2-m...)
Affinity DataIC50:  3.40E+4nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cells overexpressing Ikr channel proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed