Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 3384
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32447(Benzo[c][2,7]naphthyridine, 39)
Affinity DataIC50:  24nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32435(Benzo[c][2,7]naphthyridine, 28)
Affinity DataIC50:  26nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32450(Benzo[c][2,7]naphthyridine, 42)
Affinity DataIC50:  30nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32430(Benzo[c][2,7]naphthyridine, 24)
Affinity DataIC50:  35nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32433(Benzo[c][2,7]naphthyridine, 14)
Affinity DataIC50:  43nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32444(Benzo[c][2,7]naphthyridine, 36)
Affinity DataIC50:  47nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32449(Benzo[c][2,7]naphthyridine, 41)
Affinity DataIC50:  51nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32436(Benzo[c][2,7]naphthyridine, 29)
Affinity DataIC50:  57nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32437(Benzo[c][2,7]naphthyridine, 30)
Affinity DataIC50:  65nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32427(Benzo[c][2,7]naphthyridine, 21)
Affinity DataIC50:  66nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32445(Benzo[c][2,7]naphthyridine, 37)
Affinity DataIC50:  67nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32422(Benzo[c][2,7]naphthyridine, 9)
Affinity DataIC50:  70nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32441(Benzo[c][2,7]naphthyridine, 33)
Affinity DataIC50:  74nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32431(Benzo[c][2,7]naphthyridine, 25)
Affinity DataIC50:  74nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32448(Benzo[c][2,7]naphthyridine, 40)
Affinity DataIC50:  91nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32425(Benzo[c][2,7]naphthyridine, 12)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32428(Benzo[c][2,7]naphthyridine, 22)
Affinity DataIC50: >100nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32423(Benzo[c][2,7]naphthyridine, 10)
Affinity DataIC50:  108nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32446(Benzo[c][2,7]naphthyridine, 38)
Affinity DataIC50:  142nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32434(Benzo[c][2,7]naphthyridine, 27)
Affinity DataIC50:  144nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32432(Benzo[c][2,7]naphthyridine, 26)
Affinity DataIC50:  146nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32440(Benzo[c][2,7]naphthyridine, 32)
Affinity DataIC50:  283nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32443(Benzo[c][2,7]naphthyridine, 35)
Affinity DataIC50:  383nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32442(Benzo[c][2,7]naphthyridine, 34)
Affinity DataIC50:  434nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32451(Benzo[c][2,7]naphthyridine, 43)
Affinity DataIC50:  505nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32438(Benzo[c][2,7]naphthyridine, 31)
Affinity DataIC50:  532nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32418(Benzo[c][2,7]naphthyridine, 5)
Affinity DataIC50:  739nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32452(Benzo[c][2,7]naphthyridine, 44)
Affinity DataIC50: >1.00E+3nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32426(Benzo[c][2,7]naphthyridine, 15)
Affinity DataIC50: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32439(Benzo[c][2,7]naphthyridine, 16)
Affinity DataIC50: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32420(Benzo[c][2,7]naphthyridine, 7)
Affinity DataIC50:  1.86E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32424(Benzo[c][2,7]naphthyridine, 11)
Affinity DataIC50:  2.03E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32421(Benzo[c][2,7]naphthyridine, 8)
Affinity DataIC50:  2.06E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32429(Benzo[c][2,7]naphthyridine, 23)
Affinity DataIC50:  6.92E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32419(Benzo[c][2,7]naphthyridine, 6)
Affinity DataIC50:  7.49E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed