Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50038972
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301365(CHEMBL570365 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301359(CHEMBL570846 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301358(CHEMBL568729 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301364(CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301362(4-(2-methoxyethylamino)-N-(5-(7-methoxyquinolin-4-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301363(1-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301357(CHEMBL572237 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301366(5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301366(5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301367(CHEMBL570381 | N-(5-(7-methoxyquinolin-4-yloxy)pyr...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PKRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301368(CHEMBL570189 | N-(5-(7-methoxyquinolin-4-yloxy)pyr...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PEKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Jak2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Jak1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of TYK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301364(CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301359(CHEMBL570846 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301361(CHEMBL570647 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301358(CHEMBL568729 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301366(5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301360(CHEMBL570643 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301361(CHEMBL570647 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301368(CHEMBL570189 | N-(5-(7-methoxyquinolin-4-yloxy)pyr...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301367(CHEMBL570381 | N-(5-(7-methoxyquinolin-4-yloxy)pyr...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301365(CHEMBL570365 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301364(CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301363(1-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301362(4-(2-methoxyethylamino)-N-(5-(7-methoxyquinolin-4-...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301357(CHEMBL572237 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50301360(CHEMBL570643 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301364(CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in alkaline phosphatase levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301364(CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in osteocalcin levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in alkaline phosphatase levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301364(CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in osteocalcin levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed