Compile Data Set for Download or QSAR
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Found 24 Enz. Inhib. hit(s) with all data for entry = 50030789
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301400(4-(3,4,5-tribromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c...)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301402(4-(4-bromo-5-chloro-1H-pyrrol-2-yl)-1H-imidazo[4,5...)
Affinity DataIC50:  2.02E+3nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301414(4-(3,5-dibromo-4-phenethyl-1H-pyrrol-2-yl)-1H-imid...)
Affinity DataIC50:  2.99E+3nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50215926(4-(4,5-dibromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]py...)
Affinity DataIC50:  3.66E+3nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301401(4-(4,5-dichloro-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]p...)
Affinity DataIC50:  5.02E+3nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301409(4-(3,5-dibromo-4-methyl-1H-pyrrol-2-yl)-1H-imidazo...)
Affinity DataIC50:  5.02E+3nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301413(4-(5-bromo-4-phenethyl-1H-pyrrol-2-yl)-1H-imidazo[...)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301410(4-(5-bromo-4-phenyl-1H-pyrrol-2-yl)-1H-imidazo[4,5...)
Affinity DataIC50:  1.87E+4nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301411(4-(4-benzyl-5-bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301412(4-(4-benzyl-3,5-dibromo-1H-pyrrol-2-yl)-1H-imidazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301415(4-(3,5-dibromo-4-(2-(trifluoromethyl)phenethyl)-1H...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301416(4-(3,5-dibromo-4-(3-(trifluoromethyl)phenethyl)-1H...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301417(4-(3,5-dibromo-4-(4-(trifluoromethyl)phenethyl)-1H...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301418(4-(5-bromo-4-(3-phenylpropyl)-1H-pyrrol-2-yl)-1H-i...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301419(4-(3,5-dibromo-4-(3-phenylpropyl)-1H-pyrrol-2-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301408(4-(5-bromo-4-methyl-1H-pyrrol-2-yl)-1H-imidazo[4,5...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301407(4-(5-(biphenyl-4-yl)-4-bromo-1H-pyrrol-2-yl)-1H-im...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301406(4-(5-(biphenyl-3-yl)-4-bromo-1H-pyrrol-2-yl)-1H-im...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301405(4-(4-bromo-5-phenyl-1H-pyrrol-2-yl)-1H-imidazo[4,5...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301404(4-(3,4-dibromo-5-methyl-1H-pyrrol-2-yl)-1H-imidazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301403(4-(4-bromo-5-methyl-1H-pyrrol-2-yl)-1H-imidazo[4,5...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50215928(4-(4-bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50301420(4-(4,5-dibromo-3-phenethyl-1H-pyrrol-2-yl)-1H-imid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50215930(4-(5-bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed