Compile Data Set for Download or QSAR
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Found 35 Enz. Inhib. hit(s) with all data for entry = 50035831
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of [3H]N-propylnorapomorphine as radioligand for Dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataIC50:  27nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM81924((R)-3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP(+/-)...)
Affinity DataIC50:  183nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM81924((R)-3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP(+/-)...)
Affinity DataIC50:  184nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50010580(4-(1-Allyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazo...)
Affinity DataIC50:  257nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataIC50:  384nMAssay Description:Inhibition of binding of [3H]SCH-23390 to Dopamine receptor D1 was determinedMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50010573(4-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazo...)
Affinity DataIC50:  411nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50010580(4-(1-Allyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazo...)
Affinity DataIC50:  440nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM81924((R)-3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP(+/-)...)
Affinity DataIC50:  590nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50007573(4-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiaz...)
Affinity DataIC50:  596nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367946(CHEMBL1203001)
Affinity DataIC50:  911nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM81924((R)-3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP(+/-)...)
Affinity DataIC50:  930nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50010573(4-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazo...)
Affinity DataIC50:  945nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50007573(4-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiaz...)
Affinity DataIC50:  958nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367941(CHEMBL1203003)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes. (36%inhibition at 10 e-6 M)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367942(CHEMBL1203006)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes. (41% inhibition at 10 e-6 M)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50010575(5-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-3H-1l...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes. (2% inhibition at 10 e-6 M)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367938(CHEMBL1203009)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes. (15% inhibition at 10 e-6 M)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50010571(CHEMBL108682 | Methyl-[4-(1-propyl-1,2,5,6-tetrahy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367947(CHEMBL1203005)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes. (25% inhibition at 10 e-6 M)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50010571(CHEMBL108682 | Methyl-[4-(1-propyl-1,2,5,6-tetrahy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes. (25% inhibition at 10 e-6 M)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367945(CHEMBL1203008)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367946(CHEMBL1203001)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367943(CHEMBL1202201)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367940(CHEMBL1203007)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367944(CHEMBL1203004)
Affinity DataIC50:  2.17E+3nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367939(CHEMBL1203002)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of [3H]haloperidol binding for Dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367940(CHEMBL1203007)
Affinity DataIC50:  3.99E+3nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367944(CHEMBL1203004)
Affinity DataIC50:  5.13E+3nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367941(CHEMBL1203003)
Affinity DataIC50:  5.33E+3nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367943(CHEMBL1202201)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50367939(CHEMBL1203002)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM81924((R)-3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP(+/-)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of binding of [3H]SCH-23390 to Dopamine receptor D1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50010580(4-(1-Allyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazo...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of binding of [3H]SCH-23390 to Dopamine receptor D1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50007573(4-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiaz...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of binding of [3H]SCH-23390 to Dopamine receptor D1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed