Compile Data Set for Download or QSAR
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Found 42 Enz. Inhib. hit(s) with all data for entry = 50031312
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310938(5-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310948(5-((3-chloro-10-methyl-9H-benzo[f]imidazo[1,5-a][1...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310947(5-((3,10-dimethyl-9H-benzo[f]imidazo[1,5-a][1,2,4]...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310937(5-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310946(10-methyl-6-((3-methylisoxazol-5-yl)methyl)-9H-ben...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50144861(3-(5-Methyl-isoxazol-3-yl)-6-(pyridin-2-ylmethoxy)...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha1beta3gamma2 receptorMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50144861(3-(5-Methyl-isoxazol-3-yl)-6-(pyridin-2-ylmethoxy)...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50144861(3-(5-Methyl-isoxazol-3-yl)-6-(pyridin-2-ylmethoxy)...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha2beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50144861(3-(5-Methyl-isoxazol-3-yl)-6-(pyridin-2-ylmethoxy)...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha3beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310945(3-methyl-5-((10-methyl-9H-benzo[f]imidazo[1,5-a][1...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310944(5-((3-methoxy-10-methyl-9H-benzo[f]imidazo[1,5-a][...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310935(3-bromo-6-(cyclopropylmethyl)-10-methyl-9H-benzo[f...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310939(3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310936(1-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310943(3-methyl-5-((10-methyl-3-(trifluoromethoxy)-9H-ben...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310942(3-bromo-6-(methoxymethyl)-10-methyl-9H-benzo[f]imi...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310941(3-bromo-6,10-dimethyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310938(5-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha3beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310938(5-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha2beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310939(3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]...)
Affinity DataKi:  132nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha3beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310939(3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]...)
Affinity DataKi:  136nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha1beta3gamma2 receptorMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310940(3-bromo-6-tert-butyl-10-methyl-9H-benzo[f]imidazo[...)
Affinity DataKi:  146nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310939(3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]...)
Affinity DataKi:  186nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha2beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310938(5-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  188nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha1beta3gamma2 receptorMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310937(5-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  277nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha3beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310937(5-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  317nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha2beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310935(3-bromo-6-(cyclopropylmethyl)-10-methyl-9H-benzo[f...)
Affinity DataKi:  407nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha2beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310935(3-bromo-6-(cyclopropylmethyl)-10-methyl-9H-benzo[f...)
Affinity DataKi:  407nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha3beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310937(5-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  469nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha1beta3gamma2 receptorMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310936(1-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  515nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha3beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310935(3-bromo-6-(cyclopropylmethyl)-10-methyl-9H-benzo[f...)
Affinity DataKi:  538nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha1beta3gamma2 receptorMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310942(3-bromo-6-(methoxymethyl)-10-methyl-9H-benzo[f]imi...)
Affinity DataKi:  592nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha3beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310942(3-bromo-6-(methoxymethyl)-10-methyl-9H-benzo[f]imi...)
Affinity DataKi:  619nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha1beta3gamma2 receptorMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310936(1-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  624nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha1beta3gamma2 receptorMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310936(1-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  669nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha2beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310942(3-bromo-6-(methoxymethyl)-10-methyl-9H-benzo[f]imi...)
Affinity DataKi:  693nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha2beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310940(3-bromo-6-tert-butyl-10-methyl-9H-benzo[f]imidazo[...)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha2beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310940(3-bromo-6-tert-butyl-10-methyl-9H-benzo[f]imidazo[...)
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha3beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310941(3-bromo-6,10-dimethyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  1.42E+3nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha1beta3gamma2 receptorMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310941(3-bromo-6,10-dimethyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  1.62E+3nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha3beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310940(3-bromo-6-tert-butyl-10-methyl-9H-benzo[f]imidazo[...)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha1beta3gamma2 receptorMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310941(3-bromo-6,10-dimethyl-9H-benzo[f]imidazo[1,5-a][1,...)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]flumazenil from GABAAalpha2beta3gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed