Compile Data Set for Download or QSAR
maximum 50k data
Found 52 Enz. Inhib. hit(s) with all data for entry = 50030606
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299031(2-(1,4'-bipiperidin-1'-yl)-6-(2-methoxypyridin-4-y...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299045(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridi...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299035(CHEMBL574387 | N-(5-(2-(1,4'-bipiperidin-1'-yl)thi...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299014(2-(1,4'-bipiperidin-1'-yl)-6-chlorothiazolo[4,5-c]...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299027(2-(1,4'-bipiperidin-1'-yl)-6-(2-fluoropyridin-4-yl...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299034(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridi...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299029(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridi...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299049(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridi...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299045(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridi...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse brain histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299035(CHEMBL574387 | N-(5-(2-(1,4'-bipiperidin-1'-yl)thi...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse brain histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299040(2-(1,4'-bipiperidin-1'-yl)-6-(2-fluoropyridin-3-yl...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299041(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridi...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299017(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridi...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299036(2-(1,4'-bipiperidin-1'-yl)-6-(pyrimidin-5-yl)thiaz...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299048(2-(1,4'-bipiperidin-1'-yl)-6-(pyrimidin-5-yl)thiaz...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299046(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridi...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299047(CHEMBL575693 | N-(5-(2-(1,4'-bipiperidin-1'-yl)thi...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299016(4-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridi...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299010(CHEMBL574614 | N-(2-(1,4'-bipiperidin-1'-yl)thiazo...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299034(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridi...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse brain histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299018(1-(3-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyr...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299013(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridine-...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299030(2-(1,4'-bipiperidin-1'-yl)-6-(6-methoxypyridin-3-y...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299038(2-(1,4'-bipiperidin-1'-yl)-6-(6-fluoropyridin-3-yl...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299008(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridine-...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299028(2-(1,4'-bipiperidin-1'-yl)-6-(2-fluoropyridin-3-yl...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299033(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridi...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299039(2-(1,4'-bipiperidin-1'-yl)-6-(2-fluoropyridin-4-yl...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299022(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridi...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299015(CHEMBL573491 | N-(2-(1,4'-bipiperidin-1'-yl)benzo[...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299020(4-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridi...)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299026(2-(1,4'-bipiperidin-1'-yl)-6-(6-fluoropyridin-3-yl...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299043(2-(1,4'-bipiperidin-1'-yl)-6-(2-methoxypyridin-4-y...)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299036(2-(1,4'-bipiperidin-1'-yl)-6-(pyrimidin-5-yl)thiaz...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse brain histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299037(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridi...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299012(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridin-6...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299014(2-(1,4'-bipiperidin-1'-yl)-6-chlorothiazolo[4,5-c]...)
Affinity DataKi:  75nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse brain histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299007(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridin-6...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299023(1-(3-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyr...)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Mus musculus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299038(2-(1,4'-bipiperidin-1'-yl)-6-(6-fluoropyridin-3-yl...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse brain histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299042(2-(1,4'-bipiperidin-1'-yl)-6-(6-methoxypyridin-3-y...)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299044(2-(1,4'-bipiperidin-1'-yl)-6-(6-methylpyridin-3-yl...)
Affinity DataKi:  104nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299009(2-(1,4'-bipiperidin-1'-yl)-6-chlorothiazolo[4,5-b]...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299021(4-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridi...)
Affinity DataKi:  126nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299011(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridine ...)
Affinity DataKi:  128nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299032(2-(1,4'-bipiperidin-1'-yl)-6-(6-methylpyridin-3-yl...)
Affinity DataKi:  133nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299006(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridine ...)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299019(2-(1,4'-bipiperidin-1'-yl)-6-(3-methoxyphenyl)thia...)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299050(2-(1,4'-bipiperidin-1'-yl)-6-bromothiazolo[4,5-b]p...)
Affinity DataKi:  141nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299025(4-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridi...)
Affinity DataKi:  213nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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