Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50031338
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311517((R,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-aza...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311518(CHEMBL1087150 | N-(4-chlorobenzyl)-2-((2R,6R,E)-5,...)
Affinity DataEC50:  4.00E+3nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311519(CHEMBL1088172 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,...)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311520(CHEMBL1087530 | N-(4-chlorobenzyl)-2-((2R,6R,E)-5,...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50249181(CHEMBL473392 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,1...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311521(CHEMBL1081556 | N-(4-chlorobenzyl)-2-((2S,6S,E)-5,...)
Affinity DataKd:  570nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311522(CHEMBL1080649 | N-(4-chlorobenzyl)-2-((2S,6S,E)-5,...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311523(CHEMBL1081555 | N-(4-chlorobenzyl)-2-((2S,6R,E)-5,...)
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311524(CHEMBL1079558 | N-(4-chlorobenzyl)-2-((2S,6R,E)-5,...)
Affinity DataKd:  8.70E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311525(CHEMBL1081726 | N-(4-chlorobenzyl)-2-((2S,6R,E)-5,...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311526((S,E)-N-(4-chlorobenzyl)-2-(5,14-dioxo-1-oxa-4-aza...)
Affinity DataKd:  5.70E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311527((S,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-aza...)
Affinity DataKd:  2.38E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311528((S,E)-N-(4-chlorobenzyl)-2-(5,13-dioxo-1-oxa-4-aza...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311529((R,E)-N-(4-chlorobenzyl)-2-(5,14-dioxo-1-oxa-4-aza...)
Affinity DataKd:  3.82E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311517((R,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311530((R,E)-N-(4-chlorobenzyl)-2-(5,13-dioxo-1-oxa-4-aza...)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311530((R,E)-N-(4-chlorobenzyl)-2-(5,13-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  3.10E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311527((S,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  6.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311529((R,E)-N-(4-chlorobenzyl)-2-(5,14-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  3.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311528((S,E)-N-(4-chlorobenzyl)-2-(5,13-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  7.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311524(CHEMBL1079558 | N-(4-chlorobenzyl)-2-((2S,6R,E)-5,...)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311526((S,E)-N-(4-chlorobenzyl)-2-(5,14-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  6.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311521(CHEMBL1081556 | N-(4-chlorobenzyl)-2-((2S,6S,E)-5,...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50249181(CHEMBL473392 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,1...)
Affinity DataEC50:  4.00E+3nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311522(CHEMBL1080649 | N-(4-chlorobenzyl)-2-((2S,6S,E)-5,...)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311519(CHEMBL1088172 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,...)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311520(CHEMBL1087530 | N-(4-chlorobenzyl)-2-((2R,6R,E)-5,...)
Affinity DataEC50:  7.00E+3nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311518(CHEMBL1087150 | N-(4-chlorobenzyl)-2-((2R,6R,E)-5,...)
Affinity DataKd:  8.90E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed