Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 4811
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-be...)
Affinity DataKi:  0.560nM ΔG°:  -51.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  0.640nM ΔG°:  -51.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM11638(CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...)
Affinity DataKi:  0.800nM ΔG°:  -51.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM82123(Brinzolamide, BRZ)
Affinity DataKi:  0.900nM ΔG°:  -50.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM82123(Brinzolamide, BRZ)
Affinity DataKi:  3nM ΔG°:  -47.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-yl...)
Affinity DataKi:  3.40nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-be...)
Affinity DataKi:  3.5nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-be...)
Affinity DataKi:  5.10nM ΔG°:  -46.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM13054((2R,4R)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  9nM ΔG°:  -45.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM13054((2R,4R)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  10nM ΔG°:  -44.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-yl...)
Affinity DataKi:  10nM ΔG°:  -44.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  10.1nM ΔG°:  -44.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  11nM ΔG°:  -44.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  12nM ΔG°:  -44.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-be...)
Affinity DataKi:  12nM ΔG°:  -44.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-yl...)
Affinity DataKi:  13nM ΔG°:  -44.3kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-yl...)
Affinity DataKi:  14nM ΔG°:  -44.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-be...)
Affinity DataKi:  15nM ΔG°:  -43.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-be...)
Affinity DataKi:  16nM ΔG°:  -43.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  18nM ΔG°:  -43.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  23nM ΔG°:  -42.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  25nM ΔG°:  -42.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  34.1nM ΔG°:  -41.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM11638(CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...)
Affinity DataKi:  40nM ΔG°:  -41.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  250nM ΔG°:  -37.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-yl...)
Affinity DataKi:  510nM ΔG°:  -35.3kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-be...)
Affinity DataKi:  630nM ΔG°:  -34.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-yl...)
Affinity DataKi:  680nM ΔG°:  -34.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-be...)
Affinity DataKi:  750nM ΔG°:  -34.4kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-be...)
Affinity DataKi:  840nM ΔG°:  -34.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  930nM ΔG°:  -33.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  1.00E+3nM ΔG°:  -33.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM11638(CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...)
Affinity DataKi:  1.20E+4nM ΔG°:  -27.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM82123(Brinzolamide, BRZ)
Affinity DataKi:  4.50E+4nM ΔG°:  -24.4kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM13054((2R,4R)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  5.00E+4nM ΔG°:  -24.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed