Compile Data Set for Download or QSAR
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Found 84 Enz. Inhib. hit(s) with all data for entry = 50030649
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299643(2-Fluoro-4-[5-(3-hydroxyphenyl)-2-thienyl]phenol |...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299656(2-Fluoro-4-[5-(4-fluoro-3-hydroxyphenyl)thien-2-yl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299655(2-Fluoro-4-[5-(3-fluoro-5-hydroxyphenyl)thien-2-yl...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299659(4-[5-(3-Hydroxyphenyl)-2-thienyl]-2-(trifluorometh...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299651(3-Fluoro-5-[5-(4-hydroxyphenyl)-2-thienyl]phenol |...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299633(4-[5-(3-Hydroxyphenyl)-2-thienyl)-2-methyl]phenol ...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM25831(4-[2-(3-hydroxyphenyl)-1,3-thiazol-5-yl]phenol | h...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299654(4-Fluoro-1,1':4',1''-terphenyl-3,3''-diol | CHEMBL...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299653(2,6-Difluoro-4-[5-(3-hydroxyphenyl)-2-thienyl]phen...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299645(4-[5-(3-Hydroxyphenyl)-3-thienyl]-2-methylphenol |...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299647(2-Fluoro-4-[5-(3-hydroxyphenyl)-3-thienyl]phenol |...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM25850(3-[5-(4-hydroxyphenyl)thiophen-2-yl]phenol | hydro...)
Affinity DataIC50:  69nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM25855(3-[4-(4-hydroxyphenyl)thiophen-2-yl]phenol | hydro...)
Affinity DataIC50:  77nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299659(4-[5-(3-Hydroxyphenyl)-2-thienyl]-2-(trifluorometh...)
Affinity DataIC50:  97nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299658(2-Fluoro-5-[5-(4-hydroxyphenyl)-2-thienyl]phenol |...)
Affinity DataIC50:  113nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299657(3,3',3''-Thiene-2,3,5-triyltriphenol | CHEMBL57668...)
Affinity DataIC50:  119nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299644(1,1':4',1''-terphenyl-3,3''-diol | CHEMBL570117)
Affinity DataIC50:  123nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299648(CHEMBL583734 | Ethyl (2E)-3-[2-Hydroxy-5-[5-(3-hyd...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299632(4-[2-(3-Hydroxyphenyl)-1,3-thiazol-5-yl]-2-methylp...)
Affinity DataIC50:  143nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299638(4-Methyl-1,1':4',1''-terphenyl-3,4''-diol | CHEMBL...)
Affinity DataIC50:  171nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM25851(3-[5-(3-hydroxyphenyl)thiophen-2-yl]phenol | hydro...)
Affinity DataIC50:  173nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM25863(3-[4-(3-hydroxyphenyl)phenyl]phenol | hydroxypheny...)
Affinity DataIC50:  173nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299658(2-Fluoro-5-[5-(4-hydroxyphenyl)-2-thienyl]phenol |...)
Affinity DataIC50:  183nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299657(3,3',3''-Thiene-2,3,5-triyltriphenol | CHEMBL57668...)
Affinity DataIC50:  188nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299656(2-Fluoro-4-[5-(4-fluoro-3-hydroxyphenyl)thien-2-yl...)
Affinity DataIC50:  218nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299655(2-Fluoro-4-[5-(3-fluoro-5-hydroxyphenyl)thien-2-yl...)
Affinity DataIC50:  227nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299654(4-Fluoro-1,1':4',1''-terphenyl-3,3''-diol | CHEMBL...)
Affinity DataIC50:  253nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299652(CHEMBL568944 | N-(3-[5-(3-Hydroxyphenyl)-2-thienyl...)
Affinity DataIC50:  276nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299653(2,6-Difluoro-4-[5-(3-hydroxyphenyl)-2-thienyl]phen...)
Affinity DataIC50:  312nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM25847(3-(5-phenylthiophen-2-yl)phenol | hydroxyphenyl su...)
Affinity DataIC50:  342nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299652(CHEMBL568944 | N-(3-[5-(3-Hydroxyphenyl)-2-thienyl...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299636(4-[5-(3-Hydroxyphenyl)-2-thienyl]benzene-1,2-diol ...)
Affinity DataIC50:  402nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299650((2E)-3-[2-Hydroxy-5-[5-(3-hydroxyphenyl)-2-thienyl...)
Affinity DataIC50:  427nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299651(3-Fluoro-5-[5-(4-hydroxyphenyl)-2-thienyl]phenol |...)
Affinity DataIC50:  463nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299650((2E)-3-[2-Hydroxy-5-[5-(3-hydroxyphenyl)-2-thienyl...)
Affinity DataIC50:  468nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM25864(3-[4-(4-hydroxyphenyl)phenyl]phenol | hydroxypheny...)
Affinity DataIC50:  471nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299649(3,3'-(3-Phenylthiene-2,5-diyl)diphenol | CHEMBL569...)
Affinity DataIC50:  493nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299633(4-[5-(3-Hydroxyphenyl)-2-thienyl)-2-methyl]phenol ...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299648(CHEMBL583734 | Ethyl (2E)-3-[2-Hydroxy-5-[5-(3-hyd...)
Affinity DataIC50:  502nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299647(2-Fluoro-4-[5-(3-hydroxyphenyl)-3-thienyl]phenol |...)
Affinity DataIC50:  510nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299637(CHEMBL571941 | N-(3-[5-(3-Hydroxyphenyl)-2-thienyl...)
Affinity DataIC50:  523nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299635(3-[5-(3-Fluorophenyl)-2-thienyl]phenol | CHEMBL576...)
Affinity DataIC50:  535nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299646(3,3'-(3-Methylthiene-2,5-diyl]diphenol | CHEMBL572...)
Affinity DataIC50:  567nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299642(3-[2-Hydroxy-5-[5-(3-hydroxyphenyl)-2-thienyl]phen...)
Affinity DataIC50:  620nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299634(3-[5-(4-Hydroxyphenyl)-2-thienyl]-5-methylphenol |...)
Affinity DataIC50:  629nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299630(3-[5-(4-Fluorophenyl)-2-thienyl]phenol | CHEMBL570...)
Affinity DataIC50:  717nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM25851(3-[5-(3-hydroxyphenyl)thiophen-2-yl]phenol | hydro...)
Affinity DataIC50:  745nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299631(3-[5-(3,4-Difluorophenyl)-2-thienyl]phenol | CHEMB...)
Affinity DataIC50:  780nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299643(2-Fluoro-4-[5-(3-hydroxyphenyl)-2-thienyl]phenol |...)
Affinity DataIC50:  820nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50299646(3,3'-(3-Methylthiene-2,5-diyl]diphenol | CHEMBL572...)
Affinity DataIC50:  856nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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