Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50039094
TargetEstrogen receptor(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  12.5nMAssay Description:Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311679((4bR,10bS,12aS)-8-hydroxy-12a-methyl-9-phenethyl-2...)
Affinity DataIC50:  15nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311682((4bR,10bS,12aS)-8-hydroxy-12a-methyl-2,3,4,4a,5,6,...)
Affinity DataIC50:  30nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311678((4bR,10bS,12aS)-9-allyl-8-hydroxy-12a-methyl-2,3,4...)
Affinity DataIC50:  32nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311673((8R,9S,13S,14S,16S)-2-chloro-16-fluoro-3-hydroxy-1...)
Affinity DataIC50:  35nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311667((8R,9S,13S,14S)-3-hydroxy-13-methyl-2-phenethyl-7,...)
Affinity DataIC50:  47nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311666((8R,9S,13S,14S)-3-hydroxy-13-methyl-2-(phenylethyn...)
Affinity DataIC50:  56nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311675((4bR,10bS,12aS)-9-bromo-8-hydroxy-12a-methyl-2,3,4...)
Affinity DataIC50:  73nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311674((4bR,10bS,12aS)-9-chloro-8-hydroxy-12a-methyl-2,3,...)
Affinity DataIC50:  77nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311677((4bR,10bS,12aS)-8-hydroxy-9-methoxy-12a-methyl-2,3...)
Affinity DataIC50:  85nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311680((2R,4bR,10bS,12aS)-9-chloro-2-fluoro-8-hydroxy-12a...)
Affinity DataIC50:  87nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311661((8R,9S,13S,14S)-2-Ethyl-3-hydroxy-13-methyl-6,7,8,...)
Affinity DataIC50:  89nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM17289((1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7...)
Affinity DataIC50:  96nMAssay Description:Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311672((8R,9S,13S,14S,16R)-2-chloro-16-fluoro-3-hydroxy-1...)
Affinity DataIC50:  101nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM17289((1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7...)
Affinity DataIC50:  109nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311663((8R,9S,13S,14S)-2-allyl-3-hydroxy-13-methyl-7,8,9,...)
Affinity DataIC50:  109nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311671((8R,9S,13S,14S)-2-chloro-13-ethyl-3-hydroxy-7,8,9,...)
Affinity DataIC50:  121nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311676((4bR,10bS,12aS)-8-hydroxy-9-iodo-12a-methyl-2,3,4,...)
Affinity DataIC50:  123nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311681((2S,4bR,10bS,12aS)-9-chloro-2-fluoro-8-hydroxy-12a...)
Affinity DataIC50:  126nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311658((8R,9S,13S,14S)-2-chloro-3-hydroxy-13-methyl-7,8,9...)
Affinity DataIC50:  140nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311660((8R,9S,13S,14S)-3-hydroxy-13-methyl-17-oxo-7,8,9,1...)
Affinity DataIC50:  148nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311669((13S,14S,15S)-3-Hydroxy-2-methoxy-13-methyl-7,11,1...)
Affinity DataIC50:  193nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311662((8R,9S,13S,14S)-3-Hydroxy-2-methoxy-13-methyl-6,7,...)
Affinity DataIC50:  207nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311665((8R,9S,13S,14S)-3-hydroxy-13-methyl-2-pentanoyl-7,...)
Affinity DataIC50:  218nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311659((8R,9S,13S,14S)-2-Bromo-3-hydroxy-13-methyl-6,7,8,...)
Affinity DataIC50:  233nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311670((8R,9S,13S,14S)-3-hydroxy-2-methoxy-13-methyl-7,8,...)
Affinity DataIC50:  392nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311664((8R,9S,13S,14S)-3-hydroxy-13-methyl-2-propyl-7,8,9...)
Affinity DataIC50:  545nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311668((8R,9S,13S)-3-hydroxy-2-methoxy-13-methyl-7,8,9,11...)
Affinity DataIC50:  633nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311674((4bR,10bS,12aS)-9-chloro-8-hydroxy-12a-methyl-2,3,...)
Affinity DataIC50:  770nMAssay Description:Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311677((4bR,10bS,12aS)-8-hydroxy-9-methoxy-12a-methyl-2,3...)
Affinity DataIC50:  6.20E+3nMAssay Description:Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Institute Of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311662((8R,9S,13S,14S)-3-Hydroxy-2-methoxy-13-methyl-6,7,...)
Affinity DataIC50:  1.10E+4nMAssay Description:Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed