Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50031361
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311970(1-(3-(5-(4-aminothieno[2,3-d]pyrimidin-6-yl)-1-met...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311971(1-(3-(5-(4-aminothieno[2,3-d]pyrimidin-6-yl)-1-met...)
Affinity DataIC50:  340nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311976((R)-2-(4-phenyl-1-((tetrahydrofuran-2-yl)methyl)-1...)
Affinity DataIC50:  370nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311977(2-(1-(2-morpholinobenzyl)-4-phenyl-1H-imidazol-5-y...)
Affinity DataIC50:  440nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311975(2-(1-isobutyl-4-phenyl-1H-imidazol-5-yl)thiazolo[5...)
Affinity DataIC50:  490nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311974(2-(1-(cyclohexylmethyl)-4-phenyl-1H-imidazol-5-yl)...)
Affinity DataIC50:  540nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311969(1-(3-(5-(4-aminothieno[2,3-d]pyrimidin-6-yl)-1-met...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311968(6-(1-methyl-4-(3-(p-tolylthio)phenyl)-1H-imidazol-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311967(6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311972(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)thiazolo[5,4...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311973(2-(1-ethyl-4-phenyl-1H-imidazol-5-yl)thiazolo[5,4-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311972(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)thiazolo[5,4...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of FLtMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311967(6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311972(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)thiazolo[5,4...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Tie-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311967(6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of FLtMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311967(6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of Tie-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311972(2-(1-methyl-4-phenyl-1H-imidazol-5-yl)thiazolo[5,4...)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed