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Found 2 Enz. Inhib. hit(s) with all data for entry = 50031364
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Nippon Suisan Kaisha

Curated by ChEMBL
LigandPNGBDBM50312003(CHEMBL1079947 | Lorneic acid A)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of human platelet PDE5 assessed as [3H]cGMP to [3H]GMP conversion pretreated 15 mins before substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Nippon Suisan Kaisha

Curated by ChEMBL
LigandPNGBDBM50312004(CHEMBL1079948 | Lorneic acid B)
Affinity DataIC50:  8.71E+4nMAssay Description:Inhibition of human platelet PDE5 assessed as [3H]cGMP to [3H]GMP conversion pretreated 15 mins before substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed