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Found 84 Enz. Inhib. hit(s) with all data for entry = 8089
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233037(1-(4-(Biphenyl-4-ylmethoxy)phenyl)-6,6-dimethyl-1,...)
Affinity DataIC50:  12nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233034(1-(4-(2,4-Dichlorobenzyloxy)phenyl)-6,6-dimethyl-1...)
Affinity DataIC50:  18nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233036(1-(4-(4-Methoxybenzyloxy)phenyl)-6,6-dimethyl-1,6-...)
Affinity DataIC50:  19nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233032(1-(4-(3-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-d...)
Affinity DataIC50:  20nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233037(1-(4-(Biphenyl-4-ylmethoxy)phenyl)-6,6-dimethyl-1,...)
Affinity DataIC50:  26nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233034(1-(4-(2,4-Dichlorobenzyloxy)phenyl)-6,6-dimethyl-1...)
Affinity DataIC50:  29nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM50405043(1-(4-(Benzyloxy)phenyl)-6,6-dimethyl-1,6-dihydro-1...)
Affinity DataIC50:  32nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233035(1-(4-(4-Bromobenzyloxy)phenyl)-6,6-dimethyl-1,6-di...)
Affinity DataIC50:  33nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233023(2-(4-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  33nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233035(1-(4-(4-Bromobenzyloxy)phenyl)-6,6-dimethyl-1,6-di...)
Affinity DataIC50:  33nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233032(1-(4-(3-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-d...)
Affinity DataIC50:  34nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233033(1-(4-(2-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-d...)
Affinity DataIC50:  40nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233036(1-(4-(4-Methoxybenzyloxy)phenyl)-6,6-dimethyl-1,6-...)
Affinity DataIC50:  48nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233033(1-(4-(2-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-d...)
Affinity DataIC50:  73nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233023(2-(4-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  79nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM50405043(1-(4-(Benzyloxy)phenyl)-6,6-dimethyl-1,6-dihydro-1...)
Affinity DataIC50:  120nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233022(2-(3-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  169nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute Of Chemical Technology

LigandPNGBDBM233037(1-(4-(Biphenyl-4-ylmethoxy)phenyl)-6,6-dimethyl-1,...)
Affinity DataIC50:  403nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233021(2-(2-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  424nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233024(2-(3-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  523nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233022(2-(3-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  556nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute Of Chemical Technology

LigandPNGBDBM233035(1-(4-(4-Bromobenzyloxy)phenyl)-6,6-dimethyl-1,6-di...)
Affinity DataIC50:  829nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute Of Chemical Technology

LigandPNGBDBM233034(1-(4-(2,4-Dichlorobenzyloxy)phenyl)-6,6-dimethyl-1...)
Affinity DataIC50:  1.08E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute Of Chemical Technology

LigandPNGBDBM233032(1-(4-(3-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-d...)
Affinity DataIC50:  1.11E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233021(2-(2-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  1.16E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute Of Chemical Technology

LigandPNGBDBM233036(1-(4-(4-Methoxybenzyloxy)phenyl)-6,6-dimethyl-1,6-...)
Affinity DataIC50:  1.69E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233024(2-(3-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  1.94E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute Of Chemical Technology

LigandPNGBDBM233033(1-(4-(2-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-d...)
Affinity DataIC50:  2.53E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute Of Chemical Technology

LigandPNGBDBM233023(2-(4-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  2.61E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute Of Chemical Technology

LigandPNGBDBM233036(1-(4-(4-Methoxybenzyloxy)phenyl)-6,6-dimethyl-1,6-...)
Affinity DataIC50:  3.38E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute Of Chemical Technology

LigandPNGBDBM233032(1-(4-(3-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-d...)
Affinity DataIC50:  4.08E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute Of Chemical Technology

LigandPNGBDBM50405043(1-(4-(Benzyloxy)phenyl)-6,6-dimethyl-1,6-dihydro-1...)
Affinity DataIC50:  5.40E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute Of Chemical Technology

LigandPNGBDBM233022(2-(3-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  6.49E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute Of Chemical Technology

LigandPNGBDBM233035(1-(4-(4-Bromobenzyloxy)phenyl)-6,6-dimethyl-1,6-di...)
Affinity DataIC50:  7.32E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233030(N-{4-[(3-Methoxybenzyl)oxy]phenyl}imidodicarbonimi...)
Affinity DataIC50:  8.40E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute Of Chemical Technology

LigandPNGBDBM233023(2-(4-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  8.90E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233027(N-{4-[(2-Chlorobenzyl)oxy]phenyl}imidodicarbonimid...)
Affinity DataIC50:  9.95E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute Of Chemical Technology

LigandPNGBDBM233037(1-(4-(Biphenyl-4-ylmethoxy)phenyl)-6,6-dimethyl-1,...)
Affinity DataIC50:  1.02E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute Of Chemical Technology

LigandPNGBDBM233033(1-(4-(2-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-d...)
Affinity DataIC50:  1.03E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute Of Chemical Technology

LigandPNGBDBM233034(1-(4-(2,4-Dichlorobenzyloxy)phenyl)-6,6-dimethyl-1...)
Affinity DataIC50:  1.12E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute Of Chemical Technology

LigandPNGBDBM50405043(1-(4-(Benzyloxy)phenyl)-6,6-dimethyl-1,6-dihydro-1...)
Affinity DataIC50:  1.44E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233030(N-{4-[(3-Methoxybenzyl)oxy]phenyl}imidodicarbonimi...)
Affinity DataIC50:  1.47E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute Of Chemical Technology

LigandPNGBDBM233021(2-(2-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  1.54E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute Of Chemical Technology

LigandPNGBDBM233030(N-{4-[(3-Methoxybenzyl)oxy]phenyl}imidodicarbonimi...)
Affinity DataIC50:  1.55E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute Of Chemical Technology

LigandPNGBDBM233030(N-{4-[(3-Methoxybenzyl)oxy]phenyl}imidodicarbonimi...)
Affinity DataIC50:  1.55E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233027(N-{4-[(2-Chlorobenzyl)oxy]phenyl}imidodicarbonimid...)
Affinity DataIC50:  2.08E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology

LigandPNGBDBM233029(N-{4-[(4-Bromobenzyl)oxy]phenyl}imidodicarbonimidi...)
Affinity DataIC50:  2.14E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute Of Chemical Technology

LigandPNGBDBM233028(N-{4-[(2,4-Dichlorobenzyl)oxy]phenyl}imidodicarbon...)
Affinity DataIC50:  2.79E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute Of Chemical Technology

LigandPNGBDBM233024(2-(3-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  3.46E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute Of Chemical Technology

LigandPNGBDBM233022(2-(3-(4-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1(...)
Affinity DataIC50:  3.52E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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