Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50030676
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300004(2,2,2-Trifluoro-1-[5-(quinoxalin-6-yl)thiophen-2-y...)
Affinity DataIC50:  15nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299992(4-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid |...)
Affinity DataIC50:  27nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299999(1-[5-(4-Acetylphenyl)thiophen-2-yl]-2,2,2-trifluor...)
Affinity DataIC50:  29nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300001(1-[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)thiophen-2-...)
Affinity DataIC50:  37nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299993(4-[5-(Trifluoroacetyl)thiophen-2-yl]benzonitrile |...)
Affinity DataIC50:  41nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300003(3-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid |...)
Affinity DataIC50:  70nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM25163(CHEMBL497332 | N-methyl-N-(quinoxalin-6-ylmethyl)-...)
Affinity DataIC50:  89nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300002(2,2,2-Trifluoro-1-(5-phenylthiophen-2-yl)ethanone ...)
Affinity DataIC50:  170nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299995(2,2,2-Trifluoro-1-(2-phenyl-1,3-thiazol-5-yl)ethan...)
Affinity DataIC50:  210nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50246033(2,2,2-Trifluoro-1-(5-{3-[(methylsulfonyl)methyl]-1...)
Affinity DataIC50:  230nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50246034(2,2,2-Trifluoro-1-(5-{3-[(propylsulfonyl)methyl]-1...)
Affinity DataIC50:  240nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50246035(2,2,2-Trifluoro-1-(5-{3-[(thiophen-2-ylsulfonyl)me...)
Affinity DataIC50:  520nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM25163(CHEMBL497332 | N-methyl-N-(quinoxalin-6-ylmethyl)-...)
Affinity DataIC50:  580nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50246036(2,2,2-Trifluoro-1-[5-(3-{[(4-fluorobenzyl)sulfonyl...)
Affinity DataIC50:  700nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300004(2,2,2-Trifluoro-1-[5-(quinoxalin-6-yl)thiophen-2-y...)
Affinity DataIC50:  910nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299998(2,2,2-Trifluoro-1-[5-(pyridin-2-yl)thiophen-2-yl]e...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299998(2,2,2-Trifluoro-1-[5-(pyridin-2-yl)thiophen-2-yl]e...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299997(2,2,2-Trifluoro-1-[5-(4-methoxyphenyl)thiophen-2-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299997(2,2,2-Trifluoro-1-[5-(4-methoxyphenyl)thiophen-2-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299991(2,2,2-Trifluoro-1-(4-phenylthiophen-2-yl)ethanone ...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50246034(2,2,2-Trifluoro-1-(5-{3-[(propylsulfonyl)methyl]-1...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299992(4-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid |...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50246033(2,2,2-Trifluoro-1-(5-{3-[(methylsulfonyl)methyl]-1...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299993(4-[5-(Trifluoroacetyl)thiophen-2-yl]benzonitrile |...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299994(2,2,2-Trifluoro-1-[5-(3-methoxyphenyl)thiophen-2-y...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299995(2,2,2-Trifluoro-1-(2-phenyl-1,3-thiazol-5-yl)ethan...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50246035(2,2,2-Trifluoro-1-(5-{3-[(thiophen-2-ylsulfonyl)me...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300000(2,2,2-Trifluoro-1-[5-(1H-indol-5-yl)thiophen-2-yl]...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299996(2,2,2-Trifluoro-1-[5-(2-methoxyphenyl)thiophen-2-y...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50246036(2,2,2-Trifluoro-1-[5-(3-{[(4-fluorobenzyl)sulfonyl...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299991(2,2,2-Trifluoro-1-(4-phenylthiophen-2-yl)ethanone ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299996(2,2,2-Trifluoro-1-[5-(2-methoxyphenyl)thiophen-2-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299999(1-[5-(4-Acetylphenyl)thiophen-2-yl]-2,2,2-trifluor...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300000(2,2,2-Trifluoro-1-[5-(1H-indol-5-yl)thiophen-2-yl]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300001(1-[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)thiophen-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50299994(2,2,2-Trifluoro-1-[5-(3-methoxyphenyl)thiophen-2-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300003(3-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid |...)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300002(2,2,2-Trifluoro-1-(5-phenylthiophen-2-yl)ethanone ...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300003(3-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid |...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of HDAC1 in human HCT116 cells assessed as inhibition of histone-H3 deacetylation after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50246033(2,2,2-Trifluoro-1-(5-{3-[(methylsulfonyl)methyl]-1...)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of HDAC1 in human HCT116 cells assessed as inhibition of histone-H3 deacetylation after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300003(3-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid |...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of HDAC6 in human HCT116 cells assessed as alpha-tubulin hyperacetylation after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50246033(2,2,2-Trifluoro-1-(5-{3-[(methylsulfonyl)methyl]-1...)
Affinity DataEC50:  640nMAssay Description:Inhibition of HDAC6 in human HCT116 cells assessed as alpha-tubulin hyperacetylation after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed