Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50031010
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305271(5-[2-(4-Fluorophenyl)ethyl]-2,8-dimethyl-2,3,4,5-t...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305268(8-Fluoro-2-methyl-5-(2-p-tolylethyl)-2,3,4,5-tetra...)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305266(8-Fluoro-5-[2-(4-methoxyphenyl)ethyl]-2-methyl-2,3...)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305260(2-Methyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-pyri...)
Affinity DataIC50:  33nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305267(8-Fluoro-2-methyl-5-[2-(4-trifluoromethylphenyl)et...)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305263(2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyr...)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305262(8-Fluoro-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-1...)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305269(5-[2-(4-Methoxyphenyl)ethyl]-2,8-dimethyl-2,3,4,5-...)
Affinity DataIC50:  66nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305265(2-Methyl-5-phenethyl-8-trifluoromethyl-2,3,4,5-tet...)
Affinity DataIC50:  68nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305258(2,8-Dimethyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-...)
Affinity DataIC50:  70nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305258(2,8-Dimethyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-...)
Affinity DataIC50:  87nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305270(2,8-Dimethyl-5-[2-(4-trifluoromethylphenyl)ethyl]-...)
Affinity DataIC50:  98nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305264(8-Methoxy-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-...)
Affinity DataIC50:  104nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305272(2,8-Dimethyl-5-(2-p-tolylethyl)-2,3,4,5-tetrahydro...)
Affinity DataIC50:  112nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305262(8-Fluoro-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-1...)
Affinity DataIC50:  131nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305263(2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyr...)
Affinity DataIC50:  146nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305258(2,8-Dimethyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-...)
Affinity DataIC50:  154nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305261(CHEMBL589390 | Dimebolin)
Affinity DataIC50:  158nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305263(2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyr...)
Affinity DataIC50:  158nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305255(25-[(Z)-2-(4-Fluorophenyl)vinyl]-2,8-dimethyl-2,3,...)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305260(2-Methyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-pyri...)
Affinity DataIC50:  181nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305272(2,8-Dimethyl-5-(2-p-tolylethyl)-2,3,4,5-tetrahydro...)
Affinity DataIC50:  276nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305259(2-Methyl-5-((E)-styryl)-2,3,4,5-tetrahydro-1H-pyri...)
Affinity DataIC50:  345nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305253(5-[(Z)-2-(4-Methoxyphenyl)vinyl]-2,8-dimethyl-2,3,...)
Affinity DataIC50:  550nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305269(5-[2-(4-Methoxyphenyl)ethyl]-2,8-dimethyl-2,3,4,5-...)
Affinity DataIC50:  666nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305262(8-Fluoro-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-1...)
Affinity DataIC50:  692nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305256(2,8-Dimethyl-5-((Z)-2-p-tolylvinyl)-2,3,4,5-tetrah...)
Affinity DataIC50:  910nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305265(2-Methyl-5-phenethyl-8-trifluoromethyl-2,3,4,5-tet...)
Affinity DataIC50:  974nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305271(5-[2-(4-Fluorophenyl)ethyl]-2,8-dimethyl-2,3,4,5-t...)
Affinity DataIC50:  977nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305252(8-Fluoro-2-methyl-5-((Z)-styryl)-2,3,4,5-tetrahydr...)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305264(8-Methoxy-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-...)
Affinity DataIC50:  1.05E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305273(8-Fluoro-5-[2-(4-fluorophenyl)ethyl]-2-methyl-2,3,...)
Affinity DataIC50:  1.13E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305261(CHEMBL589390 | Dimebolin)
Affinity DataIC50:  1.16E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305249(8-Fluoro-2-methyl-5-((Z)-2-p-tolylvinyl)-2,3,4,5-t...)
Affinity DataIC50:  1.44E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305276(8-Fluoro-5-[(Z)-2-(4-methoxyphenyl)-vinyl]-2-methy...)
Affinity DataIC50:  1.50E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305261(CHEMBL589390 | Dimebolin)
Affinity DataIC50:  1.58E+3nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305257(2,8-Dimethyl-5-((E)-styryl)-2,3,4,5-tetrahydro-1H-...)
Affinity DataIC50:  1.68E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305250(8-Fluoro-2-methyl-5-((E)-styryl)-2,3,4,5-tetrahydr...)
Affinity DataIC50:  1.75E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305275(8-Methyl-5-[(Z)-1-methyl-2-phenylvinyl]-2-methyl-2...)
Affinity DataIC50:  1.98E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305259(2-Methyl-5-((E)-styryl)-2,3,4,5-tetrahydro-1H-pyri...)
Affinity DataIC50:  2.13E+3nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305268(8-Fluoro-2-methyl-5-(2-p-tolylethyl)-2,3,4,5-tetra...)
Affinity DataIC50:  2.27E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305266(8-Fluoro-5-[2-(4-methoxyphenyl)ethyl]-2-methyl-2,3...)
Affinity DataIC50:  2.35E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305259(2-Methyl-5-((E)-styryl)-2,3,4,5-tetrahydro-1H-pyri...)
Affinity DataIC50:  2.58E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305254(2,8-Dimethyl-5-[(Z)-2-(4-trifluoromethylphenyl)vin...)
Affinity DataIC50:  2.81E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305251(8-Fluoro-5-[(Z)-2-(4-fluorophenyl)-vinyl]-2-methyl...)
Affinity DataIC50:  2.95E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305274(8-Fluoro-5-[(Z)-1-methyl-2-phenylvinyl]-2-methyl-2...)
Affinity DataIC50:  3.72E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305270(2,8-Dimethyl-5-[2-(4-trifluoromethylphenyl)ethyl]-...)
Affinity DataIC50:  4.07E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305277(8-Fluoro-2-methyl-5-[(Z)-2-(4-trifluoromethyl-phen...)
Affinity DataIC50:  5.58E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305260(2-Methyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-pyri...)
Affinity DataIC50:  5.73E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305267(8-Fluoro-2-methyl-5-[2-(4-trifluoromethylphenyl)et...)
Affinity DataIC50:  2.07E+4nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed