Compile Data Set for Download or QSAR
maximum 50k data
Found 57 Enz. Inhib. hit(s) with all data for entry = 50031020
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305450(CHEMBL592763 | methyl (S)-4-(3-chlorophenyl)-4-((R...)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305465(CHEMBL589647 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29949(piperidine-1-carboxamide, 21l)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305454(CHEMBL591342 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305452(CHEMBL591578 | methyl 2-((R)-(3-chlorophenyl)((R)-...)
Affinity DataIC50:  0.480nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305456(CHEMBL605408 | methyl 2-((R)-((R)-1-((S)-1-amino-3...)
Affinity DataIC50:  0.480nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305466(CHEMBL592765 | methyl 2-((R)-(3-chloro-5-fluorophe...)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17950((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305457(CHEMBL591340 | methyl 2-((R)-((R)-1-((S)-1-amino-3...)
Affinity DataIC50:  0.580nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305453(CHEMBL592762 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305462(CHEMBL590623 | methyl 2-((R)-(3-chloro-2-fluorophe...)
Affinity DataIC50:  0.610nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305461(CHEMBL606238 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305463(CHEMBL590388 | methyl 2-((R)-(5-chloro-2-fluorophe...)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17950((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305452(CHEMBL591578 | methyl 2-((R)-(3-chlorophenyl)((R)-...)
Affinity DataIC50:  0.820nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305458(CHEMBL591105 | methyl 2-((R)-(3-chlorophenyl)((R)-...)
Affinity DataIC50:  0.870nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305455(CHEMBL591341 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  1.17nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305465(CHEMBL589647 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305441((3R)-3-[(1S)-4-(acetylamino)-1-(3-chlorophenyl)-1-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305442((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-propiona...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305466(CHEMBL592765 | methyl 2-((R)-(3-chloro-5-fluorophe...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305460(CHEMBL590868 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305453(CHEMBL592762 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305463(CHEMBL590388 | methyl 2-((R)-(5-chloro-2-fluorophe...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305459(CHEMBL591104 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305464(CHEMBL590866 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305456(CHEMBL605408 | methyl 2-((R)-((R)-1-((S)-1-amino-3...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305461(CHEMBL606238 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305455(CHEMBL591341 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305457(CHEMBL591340 | methyl 2-((R)-((R)-1-((S)-1-amino-3...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305462(CHEMBL590623 | methyl 2-((R)-(3-chloro-2-fluorophe...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305450(CHEMBL592763 | methyl (S)-4-(3-chlorophenyl)-4-((R...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305454(CHEMBL591342 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305460(CHEMBL590868 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305458(CHEMBL591105 | methyl 2-((R)-(3-chlorophenyl)((R)-...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29949(piperidine-1-carboxamide, 21l)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305451(CHEMBL591579 | ethyl (S)-4-(3-chlorophenyl)-4-((R)...)
Affinity DataIC50:  14nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305441((3R)-3-[(1S)-4-(acetylamino)-1-(3-chlorophenyl)-1-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305464(CHEMBL590866 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  16.6nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305444((R)-3-((S)-1-(3-chlorophenyl)-4-(cyclopropanecarbo...)
Affinity DataIC50:  17nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305459(CHEMBL591104 | methyl 2-((R)-((R)-1-((S)-1-cyclohe...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29940(piperidine-1-carboxamide, 21c)
Affinity DataIC50:  21nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305442((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-propiona...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305446((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-ureidobu...)
Affinity DataIC50:  31nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29934(piperidine-1-carboxamide, 7h)
Affinity DataIC50:  40nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305447((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-(3-methy...)
Affinity DataIC50:  46nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305449((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-(sulfamo...)
Affinity DataIC50:  46nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305443((R)-3-((S)-4-butyramido-1-(3-chlorophenyl)-1-hydro...)
Affinity DataIC50:  57nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305444((R)-3-((S)-1-(3-chlorophenyl)-4-(cyclopropanecarbo...)
Affinity DataIC50:  79nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305447((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-(3-methy...)
Affinity DataIC50:  141nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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