Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50031166
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308418(CHEMBL605824 | N-[2-(N',N'-diisopropylamin...)
Affinity DataKi:  9nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308420(CHEMBL589563 | N-[2-(Piperidinyl)ethyl]-10H-phenot...)
Affinity DataKi:  20nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308409(CHEMBL592673 | N-(Naphthalen-1-ylmethyl)-1'H-pheno...)
Affinity DataKi:  150nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308413(CHEMBL588172 | N,N-Diisopropyl-1'H-phenothiazine-1...)
Affinity DataKi:  180nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308408(CHEMBL602314 | N-(2-Phenylethyl)-1'H-phenothiazine...)
Affinity DataKi:  190nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308419(CHEMBL589536 | N-[2-(Pyrrolidinyl)ethyl]-10H-pheno...)
Affinity DataKi:  210nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308424(CHEMBL589805 | N-(3-(Methyl(phenyl)amino)propyl)-1...)
Affinity DataKi:  250nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308402(CHEMBL590537 | N-Phenyl-1'H-phenothiazine-1'-carbo...)
Affinity DataKi:  310nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308401(CHEMBL591468 | N-(Adamant-1-yl)-1'H-phenothiazine-...)
Affinity DataKi:  350nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308412(CHEMBL589063 | N,N-Dipropyl-1'H-phenothiazine-1'-c...)
Affinity DataKi:  430nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308417(CHEMBL601282 | N-[2-(N',N'-Diethylamino)ethyl]-1'H...)
Affinity DataKi:  510nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308414((1'H-Phenothiazin-1'-yl)(pyrrolidin-1-yl)methanone...)
Affinity DataKi:  560nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308420(CHEMBL589563 | N-[2-(Piperidinyl)ethyl]-10H-phenot...)
Affinity DataKi:  620nMAssay Description:Inhibition of human recombinant AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308406(CHEMBL600460 | N-o-Tolyl-1'H-phenothiazine-1'-carb...)
Affinity DataKi:  710nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308418(CHEMBL605824 | N-[2-(N',N'-diisopropylamin...)
Affinity DataKi:  810nMAssay Description:Inhibition of human recombinant AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308411(CHEMBL589062 | N,N-Diethyl-1'H-phenothiazine-1'-ca...)
Affinity DataKi:  1.05E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308415((1'H-Phenothiazin-1'-yl)(piperidin-1-yl)methanone ...)
Affinity DataKi:  1.56E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308432(CHEMBL592432 | N-Neopentyl-1'H-phenothiazine-1'-ca...)
Affinity DataKi:  2.66E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308400(CHEMBL591234 | N-Cyclohexyl-1'H-phenothiazine-1'-c...)
Affinity DataKi:  2.81E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308399(CHEMBL601297 | N-Cyclopentyl-1'H-phenothiazine-1'-...)
Affinity DataKi:  2.99E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308429(CHEMBL592185 | N-Isopropyl-1'H-phenothiazine-1'-ca...)
Affinity DataKi:  3.41E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308407(CHEMBL589078 | N-Benzyl-1'H-phenothiazine-1'-carbo...)
Affinity DataKi:  4.45E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308405(CHEMBL590779 | N-(4-Chlorophenyl)-1'H-phenothiazin...)
Affinity DataKi:  4.69E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308421(CHEMBL589564 | N-(2-Morpholinoethyl)-10H-phenothia...)
Affinity DataKi:  6.91E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308416(CHEMBL590511 | Morpholino(1'H-phenothiazin-1'-yl)m...)
Affinity DataKi:  7.10E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308422(CHEMBL589565 | N-(3-Morpholinopropyl)-10H-phenothi...)
Affinity DataKi:  7.86E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308410(CHEMBL592674 | N,N-Dimethyl-1'H-phenothiazine-1'-c...)
Affinity DataKi:  9.20E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308426(CHEMBL606338 | N-Methyl-1'H-phenothiazine-1'-carbo...)
Affinity DataKi:  9.36E+3nMAssay Description:Inhibition of human recombinant AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308403(CHEMBL601920 | N-(4-Methoxyphenyl)-1'H-phenothiazi...)
Affinity DataKi:  9.63E+3nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308398(CHEMBL591233 | N-Cyclobutyl-1'H-phenothiazine-1'-c...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308431(CHEMBL592431 | N-tert-Butyl-1'H-phenothiazine-1'-c...)
Affinity DataKi:  1.06E+4nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308404(CHEMBL590538 | N-p-Tolyl-1'H-phenothiazine-1'-carb...)
Affinity DataKi:  1.21E+4nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308417(CHEMBL601282 | N-[2-(N',N'-Diethylamino)ethyl]-1'H...)
Affinity DataKi:  1.63E+4nMAssay Description:Inhibition of human recombinant AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308423((4-Methylpiperazin-1-yl)(10H-phenothiazin-10-yl)me...)
Affinity DataKi:  1.71E+4nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308426(CHEMBL606338 | N-Methyl-1'H-phenothiazine-1'-carbo...)
Affinity DataKi:  1.83E+4nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308428(CHEMBL589789 | N-Propyl-1'H-phenothiazine-1'-carbo...)
Affinity DataKi:  2.05E+4nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308430(CHEMBL592430 | N-Butyl-1'H-phenothiazine-1'-carbox...)
Affinity DataKi:  2.47E+4nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308433(CHEMBL604046 | N-(2-Methoxyethyl)-1'H-phenothiazin...)
Affinity DataKi:  2.91E+4nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308419(CHEMBL589536 | N-[2-(Pyrrolidinyl)ethyl]-10H-pheno...)
Affinity DataKi:  2.94E+4nMAssay Description:Inhibition of human recombinant AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308427(CHEMBL600230 | N-Ethyl-1'H-phenothiazine-1'-carbox...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308434(CHEMBL591232 | N-Cyclopropyl-1'H-phenothiazine-1'-...)
Affinity DataKi:  4.25E+4nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308425(CHEMBL590298 | Phenothiazine-1'-carboxamide)
Affinity DataKi:  8.93E+4nMAssay Description:Inhibition of human recombinant AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308425(CHEMBL590298 | Phenothiazine-1'-carboxamide)
Affinity DataKi:  9.08E+4nMAssay Description:Inhibition of human plasma BuChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308410(CHEMBL592674 | N,N-Dimethyl-1'H-phenothiazine-1'-c...)
Affinity DataKi:  4.00E+5nMAssay Description:Inhibition of human recombinant AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308429(CHEMBL592185 | N-Isopropyl-1'H-phenothiazine-1'-ca...)
Affinity DataKi:  6.91E+5nMAssay Description:Inhibition of human recombinant AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50308427(CHEMBL600230 | N-Ethyl-1'H-phenothiazine-1'-carbox...)
Affinity DataKi:  1.45E+6nMAssay Description:Inhibition of human recombinant AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed