Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50031527
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314765(CHEMBL1093305 | trans-N-(2-((S)-1'-((3S,4R)-1-tert...)
Affinity DataIC50:  4.30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(CHEMBL1093304 | trans-N-(2-((R)-1'-((3S,4R)-1-tert...)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314767(CHEMBL1093307 | trans-N-(2-((S)-1'-((3R,4S)-1-tert...)
Affinity DataIC50:  40nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(CHEMBL1093304 | trans-N-(2-((R)-1'-((3S,4R)-1-tert...)
Affinity DataIC50:  84nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314766(CHEMBL1093306 | trans-N-(2-((R)-1'-((3R,4S)-1-tert...)
Affinity DataIC50:  89nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(CHEMBL1093304 | trans-N-(2-((R)-1'-((3S,4R)-1-tert...)
Affinity DataIC50:  890nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(CHEMBL1093304 | trans-N-(2-((R)-1'-((3S,4R)-1-tert...)
Affinity DataIC50:  1.94E+3nMAssay Description:Agonist activity at human MC1R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(CHEMBL1093304 | trans-N-(2-((R)-1'-((3S,4R)-1-tert...)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at human MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314765(CHEMBL1093305 | trans-N-(2-((S)-1'-((3S,4R)-1-tert...)
Affinity DataEC50:  228nMAssay Description:Agonist activity at human MC1R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314767(CHEMBL1093307 | trans-N-(2-((S)-1'-((3R,4S)-1-tert...)
Affinity DataEC50:  620nMAssay Description:Agonist activity at human MC1R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(CHEMBL1093304 | trans-N-(2-((R)-1'-((3S,4R)-1-tert...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at mouse MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314767(CHEMBL1093307 | trans-N-(2-((S)-1'-((3R,4S)-1-tert...)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314766(CHEMBL1093306 | trans-N-(2-((R)-1'-((3R,4S)-1-tert...)
Affinity DataEC50:  94nMAssay Description:Agonist activity at human MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(CHEMBL1093304 | trans-N-(2-((R)-1'-((3S,4R)-1-tert...)
Affinity DataEC50:  1.02E+3nMAssay Description:Agonist activity at human MC1R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314765(CHEMBL1093305 | trans-N-(2-((S)-1'-((3S,4R)-1-tert...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(CHEMBL1093304 | trans-N-(2-((R)-1'-((3S,4R)-1-tert...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at rat MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(CHEMBL1093304 | trans-N-(2-((R)-1'-((3S,4R)-1-tert...)
Affinity DataEC50:  997nMAssay Description:Agonist activity at rat MC3R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(CHEMBL1093304 | trans-N-(2-((R)-1'-((3S,4R)-1-tert...)
Affinity DataEC50:  351nMAssay Description:Agonist activity at human MC3R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed