Compile Data Set for Download or QSAR
maximum 50k data
Found 78 Enz. Inhib. hit(s) with all data for entry = 50031582
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315759(CHEMBL1092073 | N-[2-(Dimethylamino)ethyl]-4-[({4-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315762(CHEMBL1092402 | N-[2-(Dimethylamino)ethyl]-4-({[4-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315758(CHEMBL1092072 | N-[2-(Dimethylamino)ethyl]-N-methy...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315754(1-[4-(7-Ethyl-4-morpholin-4-yl-7H-pyrrolo[2,3-d]py...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315758(CHEMBL1092072 | N-[2-(Dimethylamino)ethyl]-N-methy...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315754(1-[4-(7-Ethyl-4-morpholin-4-yl-7H-pyrrolo[2,3-d]py...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315748(1-{4-[7-(2,2-Dimethoxyethyl)-4-morpholin-4-yl-7H-p...)
Affinity DataIC50:  1nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315746(1-[4-(4-Morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315747(1-{4-[4-Morpholin-4-yl-7-(2,2,2-trifluoroethyl)-7H...)
Affinity DataIC50:  1nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315753(1-[4-(7-Ethyl-4-morpholin-4-yl-7H-pyrrolo[2,3-d]py...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315759(CHEMBL1092073 | N-[2-(Dimethylamino)ethyl]-4-[({4-...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315761(1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}ph...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315760(1-{4-[(4-Methylpiperazin-1-yl)carbonyl]phenyl}-3-{...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315762(CHEMBL1092402 | N-[2-(Dimethylamino)ethyl]-4-({[4-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315742(1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315749(1-{4-[4-Morpholin-4-yl-7-(2-oxoethyl)-7H-pyrrolo[2...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315757(1-{4-[7-(2-Hydroxyethyl)-4-morpholin-4-yl-7H-pyrro...)
Affinity DataIC50:  2nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315760(1-{4-[(4-Methylpiperazin-1-yl)carbonyl]phenyl}-3-{...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315753(1-[4-(7-Ethyl-4-morpholin-4-yl-7H-pyrrolo[2,3-d]py...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315749(1-{4-[4-Morpholin-4-yl-7-(2-oxoethyl)-7H-pyrrolo[2...)
Affinity DataIC50:  3nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315741(1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315757(1-{4-[7-(2-Hydroxyethyl)-4-morpholin-4-yl-7H-pyrro...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315761(1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}ph...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315740(1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315756(1-{4-[4-Morpholin-4-yl-7-(2-piperazin-1-ylethyl)-7...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315750(1-{4-[4-Morpholin-4-yl-7-(2-pyrrolidin-1-ylethyl)-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315743(1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315742(1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315747(1-{4-[4-Morpholin-4-yl-7-(2,2,2-trifluoroethyl)-7H...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315752(1-{4-[7-(2-{[2-(Dimethylamino)ethyl]amino}ethyl)-4...)
Affinity DataIC50:  11nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315756(1-{4-[4-Morpholin-4-yl-7-(2-piperazin-1-ylethyl)-7...)
Affinity DataIC50:  14nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315741(1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315748(1-{4-[7-(2,2-Dimethoxyethyl)-4-morpholin-4-yl-7H-p...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315729(3-{7-[(Dimethylamino)methyl]-4-morpholin-4-yl-5H-p...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315730(CHEMBL1088790 | {3-[4-Morpholin-4-yl-7-(pyrrolidin...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315743(1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315755(1-(4-{7-[2-(4-Methylpiperazin-1-yl)ethyl]-4-morpho...)
Affinity DataIC50:  24nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315746(1-[4-(4-Morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315750(1-{4-[4-Morpholin-4-yl-7-(2-pyrrolidin-1-ylethyl)-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315744(1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315745(1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315752(1-{4-[7-(2-{[2-(Dimethylamino)ethyl]amino}ethyl)-4...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315755(1-(4-{7-[2-(4-Methylpiperazin-1-yl)ethyl]-4-morpho...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315738((3-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-7H...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315737(3-(4-Morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-2-y...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315751(1-{4-[4-Morpholin-4-yl-7-(2-piperidin-1-ylethyl)-7...)
Affinity DataIC50:  52nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315751(1-{4-[4-Morpholin-4-yl-7-(2-piperidin-1-ylethyl)-7...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315745(1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305306((3-(9-(1-benzylpiperidin-4-yl)-6-morpholino-9H-pur...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315737(3-(4-Morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-2-y...)
Affinity DataIC50:  64nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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