Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50031599
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315998(CHEMBL1090893 | N-((S)-1-((1S,2R,4R)-4-(ethyl(isop...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315992(CHEMBL1092678 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315993(CHEMBL1091605 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 45 mins in presence of 0.1 M bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315994(CHEMBL1091604 | N-(2-((1S,2R,4R)-4-(isopropyl(meth...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315989(3-fluoro-N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315993(CHEMBL1091605 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315994(CHEMBL1091604 | N-(2-((1S,2R,4R)-4-(isopropyl(meth...)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 45 mins in presence of 0.1 M bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315998(CHEMBL1090893 | N-((S)-1-((1S,2R,4R)-4-(ethyl(isop...)
Affinity DataIC50:  1.60nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 45 mins in presence of 0.5 M bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315990(CHEMBL1092748 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50316002((+/-)-tert-butyl 2-(2-((1S,2R)-2-(4-(methylthio)be...)
Affinity DataIC50:  50nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human PBMC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315997(CHEMBL1093318 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  51nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315986(CHEMBL1090562 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  99nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315991(CHEMBL1092940 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  151nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315999(CHEMBL1092739 | tert-butyl 2-((S)-1-((1S,2R)-2-(4-...)
Affinity DataIC50:  278nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human PBMC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315988(CHEMBL1090561 | N-((S)-1-((1S,2R,4R)-4-(dimethylam...)
Affinity DataIC50:  284nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50316000((+/-)-tert-butyl 2-((R)-1-((1S,2R)-2-(4-(methylthi...)
Affinity DataIC50:  312nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human PBMC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50316001(CHEMBL1092434 | tert-butyl 2-(2-((1S,2R)-2-(4-(met...)
Affinity DataIC50:  460nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human PBMC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315987(CHEMBL1093320 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315996(CHEMBL1088930 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315992(CHEMBL1092678 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315990(CHEMBL1092748 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315995((+/-)-N-(1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-...)
Affinity DataIC50:  4.50E+3nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315995((+/-)-N-(1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-...)
Affinity DataIC50:  4.50E+3nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315989(3-fluoro-N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315993(CHEMBL1091605 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315991(CHEMBL1092940 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315994(CHEMBL1091604 | N-(2-((1S,2R,4R)-4-(isopropyl(meth...)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed