Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50031778
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318942(4-(2,4-diethyl-1-(2-methoxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318939(2-(3-(4-cyanophenoxy)-2,4-diethyl-1H-pyrrol-1-yl)-...)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50:  47nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318937(4-(2,4-diethyl-1-(methylsulfonylmethyl)-1H-pyrrol-...)
Affinity DataIC50:  56nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318933(4-(2,4-dicyclopropyl-1-(methylsulfonylmethyl)-1H-p...)
Affinity DataIC50:  71nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50:  131nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318940(2-(3-(4-cyanophenoxy)-2,4-diethyl-1H-pyrrol-1-yl)a...)
Affinity DataIC50:  173nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318935(4-(2,4-diethyl-1-(3-hydroxypropyl)-1H-pyrrol-3-ylo...)
Affinity DataIC50:  204nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318944(4-(2,4-diethyl-1H-pyrrol-3-yloxy)benzonitrile | CH...)
Affinity DataIC50:  224nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318938(2-(3-(4-cyanophenoxy)-2,4-diethyl-1H-pyrrol-1-yl)-...)
Affinity DataIC50:  886nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318936(4-(1-(2-aminoethyl)-2,4-diethyl-1H-pyrrol-3-yloxy)...)
Affinity DataIC50:  1.13E+3nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318941(2-(3-(4-cyanophenoxy)-2,4-diethyl-1H-pyrrol-1-yl)a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells by alkaline phosphatase releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed