Compile Data Set for Download or QSAR
maximum 50k data
Found 70 Enz. Inhib. hit(s) with all data for entry = 50031806
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319634(CHEMBL1084892 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  12nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319634(CHEMBL1084892 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  14nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319635(CHEMBL1084106 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  19nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319636(CHEMBL1084107 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  19nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319636(CHEMBL1084107 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  26nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319635(CHEMBL1084106 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  39nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataIC50:  46nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319658((S)-2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinol...)
Affinity DataIC50:  48nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319637(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  53nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319633(2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6...)
Affinity DataIC50:  57nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319633(2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6...)
Affinity DataIC50:  59nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataIC50:  61nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase N2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Prkcl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319637(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  110nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319634(CHEMBL1084892 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Prkcl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319630((R)-2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinol...)
Affinity DataIC50:  160nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319632(CHEMBL1084890 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  180nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319657(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  210nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319654(CHEMBL1085139 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  280nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319632(CHEMBL1084890 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  320nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataIC50:  335nMAssay Description:Inhibition of PrkceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319649(CHEMBL1084052 | benzyl 1-oxo-1,2-dihydroisoquinoli...)
Affinity DataIC50:  360nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50:  400nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319655(CHEMBL1085140 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  430nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319633(2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6...)
Affinity DataIC50:  510nMAssay Description:Inhibition of Prkcl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319650(1-benzyl-3-(1-oxo-1,2-dihydroisoquinolin-6-yl)urea...)
Affinity DataIC50:  520nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50:  660nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase N2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50:  780nMAssay Description:Inhibition of Prkcl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319652(CHEMBL1085137 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319634(CHEMBL1084892 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319632(CHEMBL1084890 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Prkcl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319639(CHEMBL1086517 | N-(1-oxo-1,2-dihydroisoquinolin-6-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319633(2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319636(CHEMBL1084107 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Prkcl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319638(CHEMBL1086297 | N-(4-oxo-3,4-dihydroquinazolin-7-y...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319637(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Prkcl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of PrkceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319656(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319632(CHEMBL1084890 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319635(CHEMBL1084106 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of Prkcl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyotonin-protein kinase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319634(CHEMBL1084892 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of DMPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyotonin-protein kinase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of DMPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyotonin-protein kinase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of DMPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319637(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319636(CHEMBL1084107 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319635(CHEMBL1084106 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyotonin-protein kinase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319637(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of DMPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319632(CHEMBL1084890 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of PrkceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319633(2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of PrkceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 70 total ) | Next | Last >>
Jump to: