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Found 9 Enz. Inhib. hit(s) with all data for entry = 50031875
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50320877(4-(4-Fluorophenyl)-7,7-dimethyl-2-phenyl-4,6,7,8-t...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of PTP1B assessed as p-nitrophenolate ion production pretreated for 10 mins measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50320882(CHEMBL1165682 | Ethyl-4-(4-fluorophenyl)-7,7-dimet...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of PTP1B assessed as p-nitrophenolate ion production pretreated for 10 mins measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50320875(7,7-Dimethyl-4-(4-nitrophenyl)-2-phenyl-4,6,7,8-te...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of PTP1B assessed as p-nitrophenolate ion production pretreated for 10 mins measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50320876(4-(4-Chlorophenyl)-7,7-dimethyl-2-phenyl-4,6,7,8-t...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of PTP1B assessed as p-nitrophenolate ion production pretreated for 10 mins measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50320881(4-(Furan-2-yl)-7,7-dimethyl-2-phenyl-4,6,7,8-tetra...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of PTP1B assessed as p-nitrophenolate ion production pretreated for 10 mins measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50320879(4-(4-Fluorophenyl)-2-phenyl-4,6,7,8-tetrahydroquin...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of PTP1B assessed as p-nitrophenolate ion production pretreated for 10 mins measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50320878(4-(4-Methoxyphenyl)-7,7-dimethyl-2-phenyl-4,6,7,8-...)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of PTP1B assessed as p-nitrophenolate ion production pretreated for 10 mins measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50320883(CHEMBL1164164 | Ethyl-4-(4-bromophenyl)-7,7-dimeth...)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of PTP1B assessed as p-nitrophenolate ion production pretreated for 10 mins measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50320880(7,7-Dimethyl-2-phenyl-4-p-tolyl-4,6,7,8-tetrahydro...)
Affinity DataIC50:  1.96E+4nMAssay Description:Inhibition of PTP1B assessed as p-nitrophenolate ion production pretreated for 10 mins measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed