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Found 12 Enz. Inhib. hit(s) with all data for entry = 50039188
TargetKappa-type opioid receptor(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50013388(6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dime...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50321030(CHEMBL1163924 | N-{[(1R,9R,10S,13R)-17-(cyclopropy...)
Affinity DataKi:  0.135nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50321028((1S,2R,6S,14R,15R,16R)-3-(cyclopropylmethyl)-11,15...)
Affinity DataKi:  0.152nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50049805(CHEMBL169703 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataKi:  0.170nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50274257((2E)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-...)
Affinity DataKi:  0.195nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50321029((1R,2R,6S,14R,15R,16S)-3-(cyclopropylmethyl)-11,15...)
Affinity DataKi:  0.279nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  0.690nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50159165((2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(fura...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50321024((1R,2S,4R,5S)-dimethyl 3,7-dimethyl-9-oxo-2,4-di(p...)
Affinity DataKi:  15nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  33.7nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50321031(CHEMBL1164183 | Tyr-c[D-cys-Phe-D-Cys]-NH2)
Affinity DataKi:  38.7nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50321032((2S,5S)-2-(4-methoxyphenyl)-5-methyl-1-(3-phenylpr...)
Affinity DataKi:  39nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed