Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 50032000
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323009(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-me...)
Affinity DataIC50:  0.200nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323003(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(2...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323007(1-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-met...)
Affinity DataIC50:  0.700nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323006(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(3...)
Affinity DataIC50:  1nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323004(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(3...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323006(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(3...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataIC50:  2.5nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323005(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(3...)
Affinity DataIC50:  4.30nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323010(1'-(5-(4-chlorophenyl)-1-(2-cyanoethyl)-4-(2,4-dic...)
Affinity DataIC50:  8nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323008(1-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-met...)
Affinity DataIC50:  34nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323002(5-(5-(4'-carbamoyl-1,4'-bipiperidine-1'-carbonyl)-...)
Affinity DataIC50:  160nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323001(3-(5-(4'-carbamoyl-1,4'-bipiperidine-1'-carbonyl)-...)
Affinity DataIC50:  180nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323006(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(3...)
Affinity DataEC50:  15nMAssay Description:Antagonist activity at CB1 receptor in forskolin-stimulated human U373-MG cells assessed as inhibition of CP-55940-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed