Affinity DataIC50: 13nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 870nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Agonist activity at human MC1 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 560nMAssay Description:Agonist activity at human MC1 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 520nMAssay Description:Agonist activity at human MC1 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.20E+3nMAssay Description:Agonist activity at human MC1 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 540nMAssay Description:Agonist activity at human MC1 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 890nMAssay Description:Agonist activity at human MC1 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at human MC5 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at human MC5 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.80E+3nMAssay Description:Agonist activity at human MC5 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 710nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human MC5 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulationMore data for this Ligand-Target Pair