Compile Data Set for Download or QSAR
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Found 73 Enz. Inhib. hit(s) with all data for entry = 50032109
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50:  97nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50:  186nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322783(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
Affinity DataIC50:  226nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324625(5-[4-(Pyridin-4-ylmethyl)phenyl]-1H-indole | CHEMB...)
Affinity DataIC50:  231nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324611(4-[(4'-Hydroxybiphenyl-4-yl)methyl]pyridine | CHEM...)
Affinity DataIC50:  248nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324611(4-[(4'-Hydroxybiphenyl-4-yl)methyl]pyridine | CHEM...)
Affinity DataIC50:  251nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50:  261nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324617(4-((3',4'-Difluorobiphenyl-4-yl)methyl)pyridine | ...)
Affinity DataIC50:  273nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322783(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
Affinity DataIC50:  287nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324614(CHEMBL1215730 | N-(4'-Isonicotinoylbiphenyl-3-yl)a...)
Affinity DataIC50:  307nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324623(4-(4-(thiophen-3-yl)benzyl)pyridine | CHEMBL121473...)
Affinity DataIC50:  331nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322785(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine | CHEM...)
Affinity DataIC50:  337nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324611(4-[(4'-Hydroxybiphenyl-4-yl)methyl]pyridine | CHEM...)
Affinity DataIC50:  341nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50:  342nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322785(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine | CHEM...)
Affinity DataIC50:  367nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324616(4-(4'-Fluoro-biphenyl-4-ylmethyl)pyridine | CHEMBL...)
Affinity DataIC50:  386nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324612(4'-(Pyridin-4-ylmethyl)biphenyl-4-amine | CHEMBL12...)
Affinity DataIC50:  406nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324612(4'-(Pyridin-4-ylmethyl)biphenyl-4-amine | CHEMBL12...)
Affinity DataIC50:  408nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324624(4-(4-(thiophen-2-yl)benzyl)pyridine | CHEMBL121473...)
Affinity DataIC50:  415nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324623(4-(4-(thiophen-3-yl)benzyl)pyridine | CHEMBL121473...)
Affinity DataIC50:  422nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324627(6-[4-(Pyridin-4-ylmethyl)phenyl]naphthalen-2-ol | ...)
Affinity DataIC50:  438nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324625(5-[4-(Pyridin-4-ylmethyl)phenyl]-1H-indole | CHEMB...)
Affinity DataIC50:  469nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324616(4-(4'-Fluoro-biphenyl-4-ylmethyl)pyridine | CHEMBL...)
Affinity DataIC50:  515nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324612(4'-(Pyridin-4-ylmethyl)biphenyl-4-amine | CHEMBL12...)
Affinity DataIC50:  522nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50:  538nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324614(CHEMBL1215730 | N-(4'-Isonicotinoylbiphenyl-3-yl)a...)
Affinity DataIC50:  567nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324623(4-(4-(thiophen-3-yl)benzyl)pyridine | CHEMBL121473...)
Affinity DataIC50:  577nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324617(4-((3',4'-Difluorobiphenyl-4-yl)methyl)pyridine | ...)
Affinity DataIC50:  598nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324627(6-[4-(Pyridin-4-ylmethyl)phenyl]naphthalen-2-ol | ...)
Affinity DataIC50:  627nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324624(4-(4-(thiophen-2-yl)benzyl)pyridine | CHEMBL121473...)
Affinity DataIC50:  647nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50:  663nMAssay Description:Inhibition of human placental CYP19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324616(4-(4'-Fluoro-biphenyl-4-ylmethyl)pyridine | CHEMBL...)
Affinity DataIC50:  668nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324625(5-[4-(Pyridin-4-ylmethyl)phenyl]-1H-indole | CHEMB...)
Affinity DataIC50:  760nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324624(4-(4-(thiophen-2-yl)benzyl)pyridine | CHEMBL121473...)
Affinity DataIC50:  796nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50:  850nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324614(CHEMBL1215730 | N-(4'-Isonicotinoylbiphenyl-3-yl)a...)
Affinity DataIC50:  876nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50:  896nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322785(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine | CHEM...)
Affinity DataIC50:  902nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322783(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
Affinity DataIC50:  921nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324616(4-(4'-Fluoro-biphenyl-4-ylmethyl)pyridine | CHEMBL...)
Affinity DataIC50:  928nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  948nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324627(6-[4-(Pyridin-4-ylmethyl)phenyl]naphthalen-2-ol | ...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324627(6-[4-(Pyridin-4-ylmethyl)phenyl]naphthalen-2-ol | ...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324619(CHEMBL1214662 | tert-Butyl 4'-(pyridin-4-ylmethyl)...)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322783(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
Affinity DataIC50:  1.52E+3nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324608(4-[1-(4'-Methoxybiphenyl-4-yl)propyl]pyridine | CH...)
Affinity DataIC50:  1.61E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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