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Found 69 Enz. Inhib. hit(s) with all data for entry = 50032193
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325788(2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325790(CHEMBL1224717 | methyl 2-(4-((8-(3-methoxyphenyl)q...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174022((E)-8-(3-(2-(3-methyl-1,2,4-oxadiazol-5-yl)-2-(4-(...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325787(8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfony...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325800(3-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174022((E)-8-(3-(2-(3-methyl-1,2,4-oxadiazol-5-yl)-2-(4-(...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174022((E)-8-(3-(2-(3-methyl-1,2,4-oxadiazol-5-yl)-2-(4-(...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174017(8-(3-(2-(3-methylcyclopenta-1,3-dienyl)-2-(4-(meth...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325794(3-(4-((8-(3-methoxyphenyl)quinolin-6-yl)methoxy)ph...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174017(8-(3-(2-(3-methylcyclopenta-1,3-dienyl)-2-(4-(meth...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174017(8-(3-(2-(3-methylcyclopenta-1,3-dienyl)-2-(4-(meth...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174017(8-(3-(2-(3-methylcyclopenta-1,3-dienyl)-2-(4-(meth...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325798(3-(4-((8-(3-ethoxyphenyl)quinolin-6-yl)methoxy)phe...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325790(CHEMBL1224717 | methyl 2-(4-((8-(3-methoxyphenyl)q...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325791(6-((2-chlorophenoxy)methyl)-8-(3-methoxyphenyl)qui...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325788(2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325790(CHEMBL1224717 | methyl 2-(4-((8-(3-methoxyphenyl)q...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325788(2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174022((E)-8-(3-(2-(3-methyl-1,2,4-oxadiazol-5-yl)-2-(4-(...)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325789(8-(3-methoxyphenyl)-6-(2-(methylsulfonyl)propan-2-...)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325789(8-(3-methoxyphenyl)-6-(2-(methylsulfonyl)propan-2-...)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325797(3-(4-((8-(3-fluorophenyl)quinolin-6-yl)methoxy)phe...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325789(8-(3-methoxyphenyl)-6-(2-(methylsulfonyl)propan-2-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325792(6-((3-chlorophenoxy)methyl)-8-(3-methoxyphenyl)qui...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325787(8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfony...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325787(8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfony...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325796(3-(4-((8-(3-(trifluoromethoxy)phenyl)quinolin-6-yl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325799(3-(4-((8-m-tolylquinolin-6-yl)methoxy)phenyl)propa...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325795(3-(4-((8-phenylquinolin-6-yl)methoxy)phenyl)propan...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325790(CHEMBL1224717 | methyl 2-(4-((8-(3-methoxyphenyl)q...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325788(2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325787(8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfony...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325798(3-(4-((8-(3-ethoxyphenyl)quinolin-6-yl)methoxy)phe...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325793(8-(3-methoxyphenyl)-6-((4-(trifluoromethyl)phenoxy...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325800(3-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325800(3-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325789(8-(3-methoxyphenyl)-6-(2-(methylsulfonyl)propan-2-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325794(3-(4-((8-(3-methoxyphenyl)quinolin-6-yl)methoxy)ph...)
Affinity DataIC50:  87nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325791(6-((2-chlorophenoxy)methyl)-8-(3-methoxyphenyl)qui...)
Affinity DataIC50:  87nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325797(3-(4-((8-(3-fluorophenyl)quinolin-6-yl)methoxy)phe...)
Affinity DataIC50:  93nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325796(3-(4-((8-(3-(trifluoromethoxy)phenyl)quinolin-6-yl...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325792(6-((3-chlorophenoxy)methyl)-8-(3-methoxyphenyl)qui...)
Affinity DataIC50:  102nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325800(3-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  103nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325795(3-(4-((8-phenylquinolin-6-yl)methoxy)phenyl)propan...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325794(3-(4-((8-(3-methoxyphenyl)quinolin-6-yl)methoxy)ph...)
Affinity DataIC50:  122nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325791(6-((2-chlorophenoxy)methyl)-8-(3-methoxyphenyl)qui...)
Affinity DataIC50:  126nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  151nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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