Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50032360
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327720(1-octyl-3-(pyrrolidin-1-ylmethyl)-5-m-tolyl-1H-ind...)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327731(CHEMBL1257625 | N-ethyl-N-((1-octyl-5-p-tolyl-1H-i...)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327730(CHEMBL1257624 | N-ethyl-N-((1-octyl-5-o-tolyl-1H-i...)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327721(1-octyl-3-(piperidin-1-ylmethyl)-5-m-tolyl-1H-indo...)
Affinity DataIC50:  700nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327716(CHEMBL1258659 | N-ethyl-N-((1-octyl-5-m-tolyl-1H-i...)
Affinity DataIC50:  700nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327714((1-octyl-5-m-tolyl-1H-indol-3-yl)methanamine | CHE...)
Affinity DataIC50:  700nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327718(CHEMBL1258775 | N-((1-octyl-5-m-tolyl-1H-indol-3-y...)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327740(CHEMBL1258097 | N,N-diethyl-2-(5-(3-methoxyphenyl)...)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327722(3-((4-methylpiperazin-1-yl)methyl)-1-octyl-5-m-tol...)
Affinity DataIC50:  900nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327719(CHEMBL1258776 | N-methyl-N-((1-octyl-5-m-tolyl-1H-...)
Affinity DataIC50:  900nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327697(2-(1-octyl-5-o-tolyl-1H-indol-3-yl)acetamide | CHE...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327707(2-(1-(3,7-dimethylocta-2,6-dienyl)-5-m-tolyl-1H-in...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327741(2-(5-(3-ethoxyphenyl)-1-octyl-1H-indol-3-yl)-N,N-d...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327698(2-(1-octyl-5-p-tolyl-1H-indol-3-yl)acetamide | CHE...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327711(2-(1-octyl-5-m-tolyl-1H-indol-3-yl)-1-(pyrrolidin-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327729(CHEMBL1257507 | N-((1-octyl-5-m-tolyl-1H-indol-3-y...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327725(3-(1-octyl-5-m-tolyl-1H-indol-3-yl)propanamide | C...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327715(CHEMBL1258548 | N,N-dimethyl-1-(1-octyl-5-m-tolyl-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327700(2-(5-(3-ethoxyphenyl)-1-octyl-1H-indol-3-yl)acetam...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327710(CHEMBL1258326 | N,N-diethyl-2-(1-octyl-5-m-tolyl-1...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327709(CHEMBL1258210 | N,N-dimethyl-2-(1-octyl-5-m-tolyl-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327696(2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetamide | CHE...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327717(CHEMBL1258660 | N-isopropyl-N-((1-octyl-5-m-tolyl-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327713(1-(4-methylpiperazin-1-yl)-2-(1-octyl-5-m-tolyl-1H...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327728(CHEMBL1257506 | N-((1-octyl-5-m-tolyl-1H-indol-3-y...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327701(2-(1-octyl-5-phenyl-1H-indol-3-yl)acetamide | CHEM...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327712(2-(1-octyl-5-m-tolyl-1H-indol-3-yl)-1-(piperidin-1...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327699(2-(5-(3-methoxyphenyl)-1-octyl-1H-indol-3-yl)aceta...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327735(4-((1-(3-methylbut-2-enyl)-5-m-tolyl-1H-indol-3-yl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327734(1-(3-methylbut-2-enyl)-3-(piperidin-1-ylmethyl)-5-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327733(CHEMBL1257748 | N-ethyl-N-((1-(3-methylbut-2-enyl)...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327705(2-(1-(3-(trifluoromethyl)benzyl)-5-m-tolyl-1H-indo...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327723(4-((1-octyl-5-m-tolyl-1H-indol-3-yl)methyl)morphol...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327738(CHEMBL1257981 | N-ethyl-N-((5-fluoro-1-octyl-1H-in...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327702(2-(1-octyl-1H-indol-3-yl)acetamide | CHEMBL1257979)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327703(2-(5-fluoro-1-octyl-1H-indol-3-yl)acetamide | CHEM...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327706(2-(1-(2-methylbuta-1,3-dienyl)-5-m-tolyl-1H-indol-...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327724(1-octyl-5-m-tolyl-1H-indole-3-carboxamide | CHEMBL...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327704(2-(5-m-tolyl-1H-indol-3-yl)acetamide | CHEMBL42768...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327739(CHEMBL1257982 | N-ethyl-N-((5-fluoro-1-(3-methylbu...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327736(CHEMBL1255906 | N-ethyl-N-((1-(3-methylbut-2-enyl)...)
Affinity DataIC50:  6.70E+4nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327737(2-(5-fluoro-1-(3-methylbut-2-enyl)-1H-indol-3-yl)a...)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327726(CHEMBL1257397 | methyl 2-(1-octyl-5-m-tolyl-1H-ind...)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327732(1-(3-methylbut-2-enyl)-5-m-tolyl-1H-indole | CHEMB...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327708(1-octyl-5-m-tolyl-1H-indole | CHEMBL1258209)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327727(CHEMBL1257398 | ethyl 2-(1-octyl-5-m-tolyl-1H-indo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed