Compile Data Set for Download or QSAR
maximum 50k data
Found 99 Enz. Inhib. hit(s) with all data for entry = 50032418
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328867(CHEMBL1269698 | rac-5-chloro-4-((N-cyclopropyl-4-(...)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328846((3R,4S)-N-(2-chloro-5-(2-(2,2-difluoroethylamino)e...)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328861(CHEMBL1269696 | methyl 4-chloro-3-(((3R,4S)-N-cycl...)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328856((3R,4S)-N-(2-chloro-5-(3-(methylamino)-3-oxopropyl...)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328844((3R,4S)-N-(2-chloro-5-((2-fluoroethylamino)methyl)...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328852((3R,4S)-N-(2-chloro-5-(2-methoxyethyl)benzyl)-N-cy...)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328852((3R,4S)-N-(2-chloro-5-(2-methoxyethyl)benzyl)-N-cy...)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328866(CHEMBL1270761 | rac-N-cyclopropyl-4-(4-(2-(2,6-dic...)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328855((3R,4S)-N-(5-(2-acetamidoethyl)-2-chlorobenzyl)-N-...)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328853((3R,4S)-N-(2-chloro-5-(3-methoxypropyl)benzyl)-N-c...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328853((3R,4S)-N-(2-chloro-5-(3-methoxypropyl)benzyl)-N-c...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328865((3S,4R)-N-(2-chloro-5-(2-methoxyethyl)benzyl)-N-cy...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328862((3R,4S)-N-((5-chloro-2-(3-methoxypropyl)pyridin-4-...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328843((3R,4S)-N-(2-chloro-5-((2,2-difluoroethylamino)met...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328854(CHEMBL1270661 | rac-N-cyclopropyl-4-(4-(2-(2,6-dic...)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328845((3R,4S)-N-(2-chloro-5-((cyclopropylamino)methyl)be...)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328848((3R,4S)-N-(2-chloro-5-(2-(ethylamino)ethyl)benzyl)...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328857((3R,4S)-N-(2-chloro-5-(2-(3,3,3-trifluoropropanami...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328867(CHEMBL1269698 | rac-5-chloro-4-((N-cyclopropyl-4-(...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328847((3R,4S)-N-(2-chloro-5-(2-(cyclopropylamino)ethyl)b...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328850((3R,4S)-N-(2-chloro-5-((methylamino)methyl)benzyl)...)
Affinity DataIC50:  1.39nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328850((3R,4S)-N-(2-chloro-5-((methylamino)methyl)benzyl)...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328855((3R,4S)-N-(5-(2-acetamidoethyl)-2-chlorobenzyl)-N-...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328856((3R,4S)-N-(2-chloro-5-(3-(methylamino)-3-oxopropyl...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328861(CHEMBL1269696 | methyl 4-chloro-3-(((3R,4S)-N-cycl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328849((3R,4S)-N-(2-chloro-5-((ethylamino)methyl)benzyl)-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328858((3R,4S)-N-(2-chloro-5-(2-(ethylamino)-2-oxoethyl)b...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328858((3R,4S)-N-(2-chloro-5-(2-(ethylamino)-2-oxoethyl)b...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328871((3R,4S)-N-(2-chloro-5-(cyclopropanecarboxamidometh...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328871((3R,4S)-N-(2-chloro-5-(cyclopropanecarboxamidometh...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328846((3R,4S)-N-(2-chloro-5-(2-(2,2-difluoroethylamino)e...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328874((3R,4S)-N-(2-chloro-5-(2-(methylamino)-2-oxoethyl)...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328874((3R,4S)-N-(2-chloro-5-(2-(methylamino)-2-oxoethyl)...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328872((3R,4S)-N-(2-chloro-5-(2-(cyclopropylamino)-2-oxoe...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328872((3R,4S)-N-(2-chloro-5-(2-(cyclopropylamino)-2-oxoe...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328862((3R,4S)-N-((5-chloro-2-(3-methoxypropyl)pyridin-4-...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328875((3R,4S)-N-(5-(2-(2-tert-butoxyacetamido)ethyl)-2-c...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328875((3R,4S)-N-(5-(2-(2-tert-butoxyacetamido)ethyl)-2-c...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328851((3R,4S)-N-(2-chloro-5-(2-(methylamino)ethyl)benzyl...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328851((3R,4S)-N-(2-chloro-5-(2-(methylamino)ethyl)benzyl...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328859((3R,4S)-N-(5-(acetamidomethyl)-2-chlorobenzyl)-N-c...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328859((3R,4S)-N-(5-(acetamidomethyl)-2-chlorobenzyl)-N-c...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328870(4-chloro-3-(((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-di...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328870(4-chloro-3-(((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-di...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328873((3R,4S)-N-(2-chloro-5-(propionamidomethyl)benzyl)-...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328873((3R,4S)-N-(2-chloro-5-(propionamidomethyl)benzyl)-...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328865((3S,4R)-N-(2-chloro-5-(2-methoxyethyl)benzyl)-N-cy...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328860((3R,4S)-N-(2-chloro-5-((3,3,3-trifluoropropanamido...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328860((3R,4S)-N-(2-chloro-5-((3,3,3-trifluoropropanamido...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328868(4-chloro-3-(((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-di...)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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