Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50032434
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50329174(CHEMBL1269644 | N-(((R)-2,3-dihydro-1H-inden-1-yl)...)
Affinity DataKi:  0.0370nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50329172(CHEMBL1270291 | N-(((S)-2'-oxo-1',2',6,8-tetrahydr...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50329175(CHEMBL1269645 | N-(((R)-2,3-dihydro-1H-inden-1-yl)...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50329173(CHEMBL1270391 | N-((R)-1-(3,5-difluorophenyl)ethyl...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50329176(CHEMBL1269646 | N-(((R)-2,3-dihydro-1H-inden-1-yl)...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50329177((S)-3-(((S)-6-(3,5-difluorophenyl)-3,3-dimethyl-2-...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50329171((S)-N-(3,5-difluorobenzyl)-N-((2'-oxo-1',2',6,8-te...)
Affinity DataKi:  0.690nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50329170((S)-N-benzyl-N-((2'-oxo-1',2',6,8-tetrahydrospiro[...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50301954((S)-N-benzyl-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydr...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50329167(CHEMBL1269977 | N-benzyl-N-((3'-methyl-2',5'-dioxo...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50329169((R)-N-benzyl-N-((3'-methyl-2',5'-dioxo-6,8-dihydro...)
Affinity DataKi:  12nMAssay Description:Binding affinity to human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50329168(CHEMBL1269978 | N-benzyl-N-((3'-methyl-2',5'-dioxo...)
Affinity DataKi:  35nMAssay Description:Binding affinity to human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed