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Found 14 Enz. Inhib. hit(s) with all data for entry = 50032447
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329397(CHEMBL1269648 | N-(4-Ethylphenyl)-5-methylbenzo[d]...)
Affinity DataIC50:  120nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329394(5-Chloro-N-(4-ethylphenyl)benzo[d]oxazol-2-amine |...)
Affinity DataIC50:  950nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329392(CHEMBL1269619 | N-(4-Ethylphenyl)benzo[d]oxazol-2-...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329404(CHEMBL1269727 | N-(3-Bromophenyl)-5-methoxybenzo[d...)
Affinity DataIC50:  2.03E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329402(CHEMBL1269907 | N-(4-Isopropylphenyl)-5-methoxyben...)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329403(5-Methoxy-N-(4-(methylthio)phenyl)benzo[d]oxazol-2...)
Affinity DataIC50:  2.77E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329393(5-Chloro-N-phenylbenzo[d]oxazol-2-amine | CHEMBL12...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329396(5-Methyl-N-phenylbenzo[d]oxazol-2-amine | CHEMBL12...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329398(CHEMBL1269649 | N-(2-Ethylphenyl)-5-methylbenzo[d]...)
Affinity DataIC50:  5.66E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329400(CHEMBL1269704 | N-(3-Methoxyphenyl)-5-methylbenzo[...)
Affinity DataIC50:  6.83E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329399(6-Methyl-N-(4-(methylthio)phenyl)benzo[d]oxazol-2-...)
Affinity DataIC50:  7.31E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329401(5-Methoxy-N-phenylbenzo[d]oxazol-2-amine | CHEMBL1...)
Affinity DataIC50:  7.88E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM49481(1,3-benzoxazol-2-yl(phenyl)amine | CHEMBL1269508 |...)
Affinity DataIC50:  8.91E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329395(CHEMBL1269906 | N-(4-Ethylphenyl)-5-nitrobenzo[d]o...)
Affinity DataIC50:  2.39E+4nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed