Compile Data Set for Download or QSAR
maximum 50k data
Found 56 Enz. Inhib. hit(s) with all data for entry = 50032529
TargetSerine/threonine-protein kinase Nek1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330575((-)-(2R,3R,4R)-1-(3-Amino-6-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  170nMT: 2°CAssay Description:Inhibition of NEK1 after 1 hr at room temperature by caliper methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330575((-)-(2R,3R,4R)-1-(3-Amino-6-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  200nMAssay Description:Inhibition of NEK2 assessed as inhibition of substrate phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330575((-)-(2R,3R,4R)-1-(3-Amino-6-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  230nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330575((-)-(2R,3R,4R)-1-(3-Amino-6-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  300nMAssay Description:Inhibition of NEK2 assessed as inhibition of substrate phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330578(1-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  410nMAssay Description:Inhibition of NEK2 autophosphorylation after 2 hrs by DELFIA assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330579(4-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  710nMAssay Description:Inhibition of NEK2 autophosphorylation after 2 hrs by DELFIA assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330595((+)-(3R,4R)-1-(3-Amino-6-(3,4,5-trimethoxyphenyl)p...)
Affinity DataIC50:  720nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330595((+)-(3R,4R)-1-(3-Amino-6-(3,4,5-trimethoxyphenyl)p...)
Affinity DataIC50:  720nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330574(1-(3-amino-6-(3-ethylthiophen-2-yl)pyrazin-2-yl)pi...)
Affinity DataIC50:  720nMAssay Description:Inhibition of NEK2 autophosphorylation after 2 hrs by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330578(1-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  870nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330578(1-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  940nMAssay Description:Inhibition of NEK2 assessed as inhibition of substrate phosphorylationMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330587((+/-)-(2R,4R)-1-(3-amino-6-(3,4,5-trimethoxyphenyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330577(4-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of NEK2 assessed as inhibition of substrate phosphorylationMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330576(4-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of NEK2 autophosphorylation after 2 hrs by DELFIA assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330586((+/-)-(2R,4R)-1-(3-amino-6-(3,4,5-trimethoxyphenyl...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330591((+/-)(3R,4R)-1-(3-amino-6-(3,4,5-trimethoxyphenyl)...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330604(1-(3-amino-6-(3-cyclopropylthiophen-2-yl)pyrazin-2...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330579(4-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of NEK2 assessed as inhibition of substrate phosphorylationMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330574(1-(3-amino-6-(3-ethylthiophen-2-yl)pyrazin-2-yl)pi...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of NEK2 assessed as inhibition of substrate phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330607(1-(3-amino-6-(3,4-dimethoxyphenyl)pyrazin-2-yl)pip...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330605(1-(3-amino-6-(3,5-dimethoxyphenyl)pyrazin-2-yl)pip...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330574(1-(3-amino-6-(3-ethylthiophen-2-yl)pyrazin-2-yl)pi...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330579(4-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330577(4-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of NEK2 assessed as inhibition of substrate phosphorylationMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330576(4-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330576(4-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of NEK2 assessed as inhibition of substrate phosphorylationMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330577(4-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330578(1-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  2.60E+3nMT: 2°CAssay Description:Inhibition of NEK1 after 1 hr at room temperature by caliper methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330592((+/-)-(3R,4S)-1-(3-amino-6-(3,4,5-trimethoxyphenyl...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330583((+)-(2S,3S,4S)-1-(3-Amino-6-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330580(1-(3-amino-6-(3-cyclopentylthiophen-2-yl)pyrazin-2...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330606(1-(3-amino-6-(3-methoxyphenyl)pyrazin-2-yl)piperid...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330581(1-(3-amino-6-(thiophen-2-yl)pyrazin-2-yl)piperidin...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330584((+/-)-(2R,4R)-1-(3-amino-6-(3,4,5-trimethoxyphenyl...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330598(1-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330585((+/-)-(2S,4R)-1-(3-amino-6-(3,4,5-trimethoxyphenyl...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330582(1-(3-amino-6-(thiophen-3-yl)pyrazin-2-yl)piperidin...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330602(1-(3-amino-6-phenylpyrazin-2-yl)piperidine-4-carbo...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330574(1-(3-amino-6-(3-ethylthiophen-2-yl)pyrazin-2-yl)pi...)
Affinity DataIC50:  8.50E+3nMT: 2°CAssay Description:Inhibition of PLK1 after 75 mins at room temperature by caliper methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330594((-)-(3S,4S)-1-(3-Amino-6-(3,4,5-trimethoxyphenyl)p...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330590((+/-)(3R,4R)-1-(3-amino-6-(3,4,5-trimethoxyphenyl)...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330589((+/-)(3R,4S)-1-(3-amino-6-(3,4,5-trimethoxyphenyl)...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330593(4-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330599(CHEMBL1277385 | methyl1-(3-amino-6-(3,4,5-trimetho...)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330575((-)-(2R,3R,4R)-1-(3-Amino-6-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  1.94E+4nMT: 2°CAssay Description:Inhibition of PLK1 after 75 mins at room temperature by caliper methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330603(1-(3-amino-6-(4-methoxyphenyl)pyrazin-2-yl)piperid...)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330574(1-(3-amino-6-(3-ethylthiophen-2-yl)pyrazin-2-yl)pi...)
Affinity DataIC50:  2.25E+4nMT: 2°CAssay Description:Inhibition of NEK1 after 1 hr at room temperature by caliper methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330578(1-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  2.26E+4nMT: 2°CAssay Description:Inhibition of PLK1 after 75 mins at room temperature by caliper methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330596(4-(3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50:  2.62E+4nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50330588((+/-)-(3R,4R)-1-(3-amino-6-(3,4,5-trimethoxyphenyl...)
Affinity DataIC50:  3.83E+4nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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