Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50032591
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331626(5-amino-N-(5-(isoxazol-3-ylcarbamoyl)-2-methylphen...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331633(5-amino-1-butyl-N-(5-(isoxazol-3-ylcarbamoyl)-2-me...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331631(5-amino-1-(4-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331630(5-amino-N-(5-(1-ethyl-1H-pyrazol-5-ylcarbamoyl)-2-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331627(5-amino-N-(5-(1-ethyl-1H-pyrazol-5-ylcarbamoyl)-2-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331625(5-amino-N-(5-(isoxazol-3-ylcarbamoyl)-2-methylphen...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331628(5-amino-1-(2-fluorophenyl)-N-(2-methyl-5-(1-methyl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331636(5-(ethylamino)-N-(5-(isoxazol-3-ylcarbamoyl)-2-met...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331637(5-(ethylamino)-N-(5-(isoxazol-3-ylcarbamoyl)-2-met...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331634(CHEMBL1289308 | N-(5-(isoxazol-3-ylcarbamoyl)-2-me...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331624(5-amino-N-(5-(1-ethyl-1H-pyrazol-5-ylcarbamoyl)-2-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331635(5-(ethylamino)-N-(5-(ethylcarbamoyl)-2-methylpheny...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331623(5-amino-N-(2-methyl-5-(1-methyl-1H-pyrazol-5-ylcar...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331632(5-amino-1-butyl-N-(2-methyl-5-(1-methyl-1H-pyrazol...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331622(5-amino-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331621(5-amino-N-(5-(ethylcarbamoyl)-2-methylphenyl)-1-ph...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331619(CHEMBL410668 | N,4-dimethyl-3-(1-phenyl-1H-pyrazol...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331620(5-amino-N-(2-methyl-5-(methylcarbamoyl)phenyl)-1-p...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Tyk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of STAT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of BtkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of DGATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of PKCzetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of PKAbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IGF-1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: >1.60E+5nMAssay Description:Inhibition of human ERG by flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed