Compile Data Set for Download or QSAR
maximum 50k data
Found 72 Enz. Inhib. hit(s) with all data for entry = 50032857
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335684(4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335683(4-fluoro-2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyr...)
Affinity DataIC50:  5nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335687(2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3...)
Affinity DataIC50:  8nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335662((S)-4-(1H-pyrazol-3-yl)-2-(4-(pyrrolidin-3-ylamino...)
Affinity DataIC50:  9nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335685(4-fluoro-2-(4-((3S,4R)-4-(hydroxymethyl)pyrrolidin...)
Affinity DataIC50:  11nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335681((S)-4-fluoro-2-(7-(2-methoxyethoxy)-4-(pyrrolidin-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335680((S)-2-(6,7-dimethoxy-4-(pyrrolidin-3-ylamino)quina...)
Affinity DataIC50:  12nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335686(2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3...)
Affinity DataIC50:  14nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335671(4-fluoro-2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyr...)
Affinity DataIC50:  21nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335678((S)-2-(6,7-dimethoxy-4-(pyrrolidin-3-ylamino)quina...)
Affinity DataIC50:  28nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335673((S)-2-(7-methoxy-4-(pyrrolidin-3-ylamino)quinazoli...)
Affinity DataIC50:  29nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335682((S)-4-fluoro-2-(6-methoxy-7-(2-methoxyethoxy)-4-(p...)
Affinity DataIC50:  30nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335670(4-fluoro-2-(4-((3S,4R)-4-(hydroxymethyl)pyrrolidin...)
Affinity DataIC50:  37nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335656((S)-4-fluoro-2-(4-(pyrrolidin-3-ylamino)quinazolin...)
Affinity DataIC50:  60nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335661((S)-4-(1H-pyrazol-4-yl)-2-(4-(pyrrolidin-3-ylamino...)
Affinity DataIC50:  65nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335675((S)-2-(7-(2-methoxyethoxy)-4-(pyrrolidin-3-ylamino...)
Affinity DataIC50:  70nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335657((S)-4-chloro-2-(4-(pyrrolidin-3-ylamino)quinazolin...)
Affinity DataIC50:  70nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335677((S)-2-(7-(3-hydroxypropyl)-4-(pyrrolidin-3-ylamino...)
Affinity DataIC50:  78nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335667(4-fluoro-2-(4-((3S,5R)-5-(hydroxymethyl)pyrrolidin...)
Affinity DataIC50:  81nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335658((S)-4-methyl-2-(4-(pyrrolidin-3-ylamino)quinazolin...)
Affinity DataIC50:  92nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335683(4-fluoro-2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyr...)
Affinity DataIC50:  105nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335679((S)-2-(6-methoxy-7-(2-methoxyethoxy)-4-(pyrrolidin...)
Affinity DataIC50:  120nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335681((S)-4-fluoro-2-(7-(2-methoxyethoxy)-4-(pyrrolidin-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335669((3R,4S)-ethyl 4-(2-(5-fluoro-2-hydroxyphenyl)quina...)
Affinity DataIC50:  154nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335648((S)-2-(4-(pyrrolidin-3-ylamino)quinazolin-2-yl)phe...)
Affinity DataIC50:  160nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335651((R)-2-(4-(piperidin-3-ylamino)quinazolin-2-yl)phen...)
Affinity DataIC50:  180nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335665((2R,4S)-4-(2-(2-hydroxyphenyl)quinazolin-4-ylamino...)
Affinity DataIC50:  181nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335684(4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL...)
Affinity DataIC50:  190nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335672((S)-2-(6-methoxy-4-(pyrrolidin-3-ylamino)quinazoli...)
Affinity DataIC50:  200nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335680((S)-2-(6,7-dimethoxy-4-(pyrrolidin-3-ylamino)quina...)
Affinity DataIC50:  200nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335660((S)-2-(4-(pyrrolidin-3-ylamino)quinazolin-2-yl)-4-...)
Affinity DataIC50:  201nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335685(4-fluoro-2-(4-((3S,4R)-4-(hydroxymethyl)pyrrolidin...)
Affinity DataIC50:  230nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335654(2-(4-(azepan-3-ylamino)quinazolin-2-yl)phenol | CH...)
Affinity DataIC50:  250nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335682((S)-4-fluoro-2-(6-methoxy-7-(2-methoxyethoxy)-4-(p...)
Affinity DataIC50:  260nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335674((S)-2-(6-(2-methoxyethoxy)-4-(pyrrolidin-3-ylamino...)
Affinity DataIC50:  280nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335679((S)-2-(6-methoxy-7-(2-methoxyethoxy)-4-(pyrrolidin...)
Affinity DataIC50:  330nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335666(4-fluoro-2-(4-((3S,5R)-5-(2-hydroxypropan-2-yl)pyr...)
Affinity DataIC50:  460nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335653((S)-2-(4-(methyl(pyrrolidin-3-yl)amino)quinazolin-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335655(2-(4-(azepan-4-ylamino)quinazolin-2-yl)phenol | CH...)
Affinity DataIC50:  510nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335676((S)-2-(6-(3-hydroxypropyl)-4-(pyrrolidin-3-ylamino...)
Affinity DataIC50:  600nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335675((S)-2-(7-(2-methoxyethoxy)-4-(pyrrolidin-3-ylamino...)
Affinity DataIC50:  850nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335646((R)-2-(4-(3-(dimethylamino)pyrrolidin-1-yl)quinazo...)
Affinity DataIC50:  860nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335673((S)-2-(7-methoxy-4-(pyrrolidin-3-ylamino)quinazoli...)
Affinity DataIC50:  870nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335678((S)-2-(6,7-dimethoxy-4-(pyrrolidin-3-ylamino)quina...)
Affinity DataIC50:  870nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335652((S)-2-(4-(1-methylpyrrolidin-3-ylamino)quinazolin-...)
Affinity DataIC50:  920nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335656((S)-4-fluoro-2-(4-(pyrrolidin-3-ylamino)quinazolin...)
Affinity DataIC50:  990nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335664((2R,4S)-methyl 4-(2-o-tolylquinazolin-4-ylamino)py...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335662((S)-4-(1H-pyrazol-3-yl)-2-(4-(pyrrolidin-3-ylamino...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335677((S)-2-(7-(3-hydroxypropyl)-4-(pyrrolidin-3-ylamino...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335650((S)-2-(4-(piperidin-3-ylamino)quinazolin-2-yl)phen...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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