Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50039394
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338500((S)-1-((1-benzyl-1H-1,2,3-triazol-5-yl)methyl)-5-(...)
Affinity DataKi:  10.5nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338491((S)-1-((1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H...)
Affinity DataKi:  14.5nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50273338((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338500((S)-1-((1-benzyl-1H-1,2,3-triazol-5-yl)methyl)-5-(...)
Affinity DataIC50:  9nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50273337((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataIC50:  16.7nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338491((S)-1-((1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H...)
Affinity DataIC50:  17nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338489((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50:  18nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338486((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50:  21nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338488((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50:  21nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338487((S)-1-((1-(biphenyl-4-yl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50:  23nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338492((S)-1-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-5-(...)
Affinity DataIC50:  30nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM10318((S)-5-{1-[2-(Phenoxymethyl)pyrrolidinyl]sulfonyl}i...)
Affinity DataIC50:  44nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338490((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50:  44nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338498((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50:  70nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338494((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50:  103nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM10305((S)-5-[1-(2-Methoxymethyl)pyrrolidinylsulfonyl]isa...)
Affinity DataIC50:  120nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338495((S)-1-((1-(biphenyl-4-yl)-1H-1,2,3-triazol-5-yl)me...)
Affinity DataIC50:  136nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338499((S)-1-((1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H...)
Affinity DataIC50:  136nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338501((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50:  207nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338496((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50:  213nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338493((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50:  243nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338497((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50:  267nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM22817(5-nitro-2,3-dihydro-1H-indole-2,3-dione | CHEMBL11...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed