Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 50033045
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50026328(CHEMBL1684207)
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50026347(CHEMBL1684197)
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338718(2-(6-fluorochroman-3-yl)-8-methoxy-6-(1H-pyrazol-4...)
Affinity DataIC50:  1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50026327(CHEMBL1684206)
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338703(CHEMBL1684208 | N-cyclopropyl-3-(4-oxo-6-(1H-pyraz...)
Affinity DataIC50:  1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338722(8-methoxy-2-((3-methoxyphenoxy)methyl)-6-(1H-pyraz...)
Affinity DataIC50:  1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50026330(CHEMBL1684210)
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50026332(CHEMBL1684209)
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50026346(CHEMBL1684201)
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338695(2-(chroman-2-yl)-6-(1H-pyrazol-4-yl)quinazolin-4(3...)
Affinity DataIC50:  2nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338698(2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)quina...)
Affinity DataIC50:  2nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338714(8-methoxy-2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338721(2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-8-methoxy-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338701(2-(6-fluorochroman-3-yl)-6-(1H-pyrazol-4-yl)quinaz...)
Affinity DataIC50:  3nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338712(3-(4-(2-(dimethylamino)ethylthio)-6-(1H-pyrazol-4-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338713(3-(4-(2-(dimethylamino)ethylthio)-6-(1H-pyrazol-4-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338719(8-methoxy-2-(6-methylchroman-3-yl)-6-(1H-pyrazol-4...)
Affinity DataIC50:  5nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338711(CHEMBL1684218 | N-cyclopropyl-3-(4-(2-(dimethylami...)
Affinity DataIC50:  6nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338700(2-(6-methylchroman-3-yl)-6-(1H-pyrazol-4-yl)quinaz...)
Affinity DataIC50:  6nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338707(2-(2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)qu...)
Affinity DataIC50:  6nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338720(8-methoxy-2-(7-methoxy-1,2,3,4-tetrahydronaphthale...)
Affinity DataIC50:  11nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338717(8-(2-(dimethylamino)ethoxy)-2-(6-methoxychroman-3-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338702(2-(6-(cyclopropanecarbonyl)chroman-3-yl)-6-(1H-pyr...)
Affinity DataIC50:  18nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338716(8-((2-(dimethylamino)ethyl)(methyl)amino)-2-(6-met...)
Affinity DataIC50:  21nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338708(2-((2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)q...)
Affinity DataIC50:  22nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338696(2-(5-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)quina...)
Affinity DataIC50:  31nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338705(2-((3-methoxyphenoxy)methyl)-6-(1H-pyrazol-4-yl)qu...)
Affinity DataIC50:  33nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338699((S)-2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)q...)
Affinity DataIC50:  87nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338715(8-fluoro-2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4...)
Affinity DataIC50:  104nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338706(2-cyclopropyl-6-(1H-pyrazol-4-yl)quinazolin-4(3H)-...)
Affinity DataIC50:  123nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338704(2-((2-methoxyphenoxy)methyl)-6-(1H-pyrazol-4-yl)qu...)
Affinity DataIC50:  188nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338709(CHEMBL1684216 | N1-(2-(6-methoxychroman-3-yl)-6-(1...)
Affinity DataIC50:  358nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338697(2-(8-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)quina...)
Affinity DataIC50:  423nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338710(2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)-N-(p...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338694(2-(2H-chromen-3-yl)-6-(1H-pyrazol-4-yl)quinazolin-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed